An anatomically comprehensive atlas of the adult human brain transcriptome

MJ Hawrylycz, ES Lein, AL Guillozet-Bongaarts… - Nature, 2012 - nature.com
Neuroanatomically precise, genome-wide maps of transcript distributions are critical
resources to complement genomic sequence data and to correlate functional and genetic …

Spatio-temporal transcriptome of the human brain

HJ Kang, YI Kawasawa, F Cheng, Y Zhu, X Xu, M Li… - Nature, 2011 - nature.com
Brain development and function depend on the precise regulation of gene expression.
However, our understanding of the complexity and dynamics of the transcriptome of the …

[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Z Yao, CTJ van Velthoven, M Kunst, M Zhang… - Nature, 2023 - nature.com
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …

The molecular cytoarchitecture of the adult mouse brain

J Langlieb, NS Sachdev, KS Balderrama, NM Nadaf… - Nature, 2023 - nature.com
The function of the mammalian brain relies upon the specification and spatial positioning of
diversely specialized cell types. Yet, the molecular identities of the cell types and their …

Transcriptional landscape of the prenatal human brain

JA Miller, SL Ding, SM Sunkin, KA Smith, L Ng… - Nature, 2014 - nature.com
The anatomical and functional architecture of the human brain is mainly determined by
prenatal transcriptional processes. We describe an anatomically comprehensive atlas of the …

Functional organization of the transcriptome in human brain

MC Oldham, G Konopka, K Iwamoto, P Langfelder… - Nature …, 2008 - nature.com
The enormous complexity of the human brain ultimately derives from a finite set of molecular
instructions encoded in the human genome. These instructions can be directly studied by …

Genome-wide atlas of gene expression in the adult mouse brain

ES Lein, MJ Hawrylycz, N Ao, M Ayres, A Bensinger… - Nature, 2007 - nature.com
Molecular approaches to understanding the functional circuitry of the nervous system
promise new insights into the relationship between genes, brain and behaviour. The cellular …

An atlas of gene regulatory elements in adult mouse cerebrum

YE Li, S Preissl, X Hou, Z Zhang, K Zhang, Y Qiu… - Nature, 2021 - nature.com
The mammalian cerebrum performs high-level sensory perception, motor control and
cognitive functions through highly specialized cortical and subcortical structures. Recent …

Molecular features driving cellular complexity of human brain evolution

E Caglayan, F Ayhan, Y Liu, RM Vollmer, E Oh… - Nature, 2023 - nature.com
Human-specific genomic changes contribute to the unique functionalities of the human
brain,,,–. The cellular heterogeneity of the human brain, and the complex regulation of gene …

An atlas of cortical arealization identifies dynamic molecular signatures

A Bhaduri, C Sandoval-Espinosa, M Otero-Garcia, I Oh… - Nature, 2021 - nature.com
The human brain is subdivided into distinct anatomical structures, including the neocortex,
which in turn encompasses dozens of distinct specialized cortical areas. Early …