Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods

B Bošnjak, SC Stein, S Willenzon, AK Cordes… - Cellular & molecular …, 2021 - nature.com
Neutralizing antibodies targeting the receptor-binding domain (RBD) of the SARS-CoV-2
spike (S) block severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry into …

A high-throughput cell-and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma

C Fenwick, P Turelli, C Pellaton, A Farina… - Science Translational …, 2021 - science.org
The detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific
antibodies in the serum of an individual indicates previous infection or vaccination …

Rapid test to assess the escape of SARS-CoV-2 variants of concern

JT Heggestad, RJ Britton, DS Kinnamon, SA Wall… - Science …, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants are concerning in
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Here, we developed a rapid …

[HTML][HTML] Performance of the rapid high-throughput automated electrochemiluminescence immunoassay targeting total antibodies to the SARS-CoV-2 spike protein …

KR Rus, M Korva, N Knap, TA Županc… - Journal of Clinical …, 2021 - Elsevier
Background Neutralization tests (NT) are the gold standard for detecting and quantifying anti-
SARS-CoV-2 neutralizing antibodies (NAb), but their complexity restricts them to research …

SARS-CoV-2 neutralizing antibodies in patients with varying severity of acute COVID-19 illness

C Jeewandara, D Jayathilaka, L Gomes… - Scientific reports, 2021 - nature.com
In order to support vaccine development, and to aid convalescent plasma therapy, it would
be important to understand the kinetics, timing and persistence of SARS-CoV-2 neutralizing …

Inference of SARS-CoV-2 spike-binding neutralizing antibody titers in sera from hospitalized COVID-19 patients by using commercial enzyme and chemiluminescent …

A Valdivia, I Torres, V Latorre… - European Journal of …, 2021 - Springer
Whether antibody levels measured by commercially available enzyme or chemiluminescent
immunoassays targeting the SARS-CoV-2 spike (S) protein can act as a proxy for serum …

[HTML][HTML] Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2

JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao… - Cell host & …, 2020 - cell.com
Antibody-based interventions against SARS-CoV-2 could limit morbidity, mortality, and
possibly transmission. An anticipated correlate of such countermeasures is the level of …

Evaluation of cell-based and surrogate SARS-CoV-2 neutralization assays

AM Sholukh, A Fiore-Gartland, ES Ford… - Journal of Clinical …, 2021 - Am Soc Microbiol
Determinants of protective immunity against severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection require the development of well-standardized, reproducible …

Convalescent plasma anti–SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization

E Salazar, SV Kuchipudi… - The Journal of …, 2020 - Am Soc Clin Investig
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
highlights the urgent need for assays that detect protective levels of neutralizing antibodies …

Declining levels of neutralizing antibodies against SARS-CoV-2 in convalescent COVID-19 patients one year post symptom onset

T Xiang, B Liang, Y Fang, S Lu, S Li, H Wang… - Frontiers in …, 2021 - frontiersin.org
Major advances have been made in understanding the dynamics of humoral immunity
briefly after the acute coronavirus disease 2019 (COVID-19). However, knowledge …