Hyperinflammatory response in COVID-19: a systematic review

MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …

[HTML][HTML] Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients

SB Anderberg, T Luther, M Berglund, R Larsson… - Cytokine, 2021 - Elsevier
Background The infection caused by SARS CoV-2 has been postulated to induce a cytokine
storm syndrome that results in organ failure and even death in a considerable number of …

Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients

RM Elshazli, EA Toraih, A Elgaml, M El-Mowafy… - PloS one, 2020 - journals.plos.org
Objective Evidence-based characterization of the diagnostic and prognostic value of the
hematological and immunological markers related to the epidemic of Coronavirus Disease …

Factors associated with disease severity and mortality among patients with COVID-19: A systematic review and meta-analysis

V Chidambaram, NL Tun, WZ Haque, MG Majella… - PloS one, 2020 - journals.plos.org
Background Understanding the factors associated with disease severity and mortality in
Coronavirus disease (COVID-19) is imperative to effectively triage patients. We performed a …

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) infection, has emerged in China in December 2019 …

Comparative survival analysis of immunomodulatory therapy for coronavirus disease 2019 cytokine storm

S Narain, DG Stefanov, AS Chau, AG Weber, G Marder… - Chest, 2021 - Elsevier
Background Cytokine storm is a marker of coronavirus disease 2019 (COVID-19) illness
severity and increased mortality. Immunomodulatory treatments have been repurposed to …

Cytokine response in SARS-CoV-2 infection in the elderly

S Sherwani, MWA Khan - Journal of Inflammation Research, 2020 - Taylor & Francis
The last few months of 2019 witnessed the emergence, rise and rapid spread of a novel
coronavirus known as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

Immune-inflammatory parameters in COVID-19 cases: a systematic review and meta-analysis

X Feng, S Li, Q Sun, J Zhu, B Chen, M Xiong… - Frontiers in …, 2020 - frontiersin.org
Background: The recent outbreak of coronavirus disease 2019 (COVID-19) has been rapidly
spreading on a global scale and poses a great threat to human health. Acute respiratory …

The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …