A granulocytic signature identifies COVID-19 and its severity

J Vitte, AB Diallo, A Boumaza, A Lopez… - The Journal of …, 2020 - academic.oup.com
Background An unbiased approach to SARS-CoV-2–induced immune dysregulation has not
been undertaken so far. We aimed to identify previously unreported immune markers able to …

Altered cytokine levels and immune responses in patients with SARS-CoV-2 infection and related conditions

R Noroozi, W Branicki, K Pyrc, PP Łabaj, E Pospiech… - Cytokine, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic in early 2020. The infection has been associated with a wide range of clinical …

An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis

Y Liu, D Chen, J Hou, H Li, D Cao, M Guo, Y Ling… - Cytokine, 2021 - Elsevier
The hyper-inflammatory response is thought to be a major cause of acute respiratory
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …

COVID-19: inflammatory profile

Y Wang, S Perlman - Annual review of medicine, 2022 - annualreviews.org
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of
coronavirus disease 2019 (COVID-19), has resulted in a pandemic that has had widespread …

A review of treatment of coronavirus disease 2019 (COVID-19): Therapeutic repurposing and unmet clinical needs

PL Chen, NY Lee, CT Cia, WC Ko… - Frontiers in …, 2020 - frontiersin.org
For the initial phase of pandemic of coronavirus disease 2019 (COVID-19), repurposing
drugs that in vitro inhibit severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

Dysregulated innate and adaptive immune responses discriminate disease severity in COVID-19

NAF Janssen, I Grondman… - The Journal of …, 2021 - academic.oup.com
The clinical spectrum of COVID-19 varies and the differences in host response
characterizing this variation have not been fully elucidated. COVID-19 disease severity …

Incidence, clinical characteristics and prognostic factor of patients with COVID-19: a systematic review and meta-analysis

C Ma, J Gu, P Hou, L Zhang, Y Bai, Z Guo, H Wu… - MedRxiv, 2020 - medrxiv.org
Abstract Background Recently, Coronavirus Disease 2019 (COVID-19) outbreak started in
Wuhan, China. Although the clinical features of COVID-19 have been reported previously …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …

Specific cytokines in the inflammatory cytokine storm of patients with COVID-19-associated acute respiratory distress syndrome and extrapulmonary multiple-organ …

J Wang, X Yang, Y Li, J Huang, J Jiang, N Su - Virology journal, 2021 - Springer
Background To date, specific cytokines associated with development of acute respiratory
distress syndrome (ARDS) and extrapulmonary multiple organ dysfunction (MOD) in COVID …

[HTML][HTML] Recent insight into SARS-CoV2 immunopathology and rationale for potential treatment and preventive strategies in COVID-19

S Lega, S Naviglio, S Volpi, A Tommasini - Vaccines, 2020 - mdpi.com
As the outbreak of the new coronavirus (SARS-CoV-2) infection is spreading globally, great
effort is being made to understand the disease pathogenesis and host factors that …