Insights into suicide and depression

NH Kalin - American Journal of Psychiatry, 2020 - Am Psychiatric Assoc
The suffering, anguish, and psychological trauma that loved ones endure when losing a
family member to suicide is devastating, and for most people, unimaginable. As mental …

Genome-wide association study of suicide death and polygenic prediction of clinical antecedents

AR Docherty, AA Shabalin, E DiBlasi… - American journal of …, 2020 - Am Psychiatric Assoc
Objective: Death by suicide is a highly preventable yet growing worldwide health crisis. To
date, there has been a lack of adequately powered genomic studies of suicide, with no …

GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

N Mullins, TB Bigdeli, AD Børglum… - American journal of …, 2019 - Am Psychiatric Assoc
Objective: More than 90% of people who attempt suicide have a psychiatric diagnosis;
however, twin and family studies suggest that the genetic etiology of suicide attempt is …

A genome-wide association study of attempted suicide

VL Willour, F Seifuddin, PB Mahon, D Jancic… - Molecular …, 2012 - nature.com
The heritable component to attempted and completed suicide is partly related to psychiatric
disorders and also partly independent of them. Although attempted suicide linkage regions …

Genetic contributions to suicidal thoughts and behaviors

E DiBlasi, J Kang, AR Docherty - Psychological medicine, 2021 - cambridge.org
Suicidal ideation, suicide attempt (SA) and suicide are significantly heritable phenotypes.
However, the extent to which these phenotypes share genetic architecture is unclear. This …

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome‐wide association and polygenic scoring study

N Mullins, N Perroud, R Uher, AW Butler… - American Journal of …, 2014 - Wiley Online Library
Epidemiological studies have recognized a genetic diathesis for suicidal behavior, which is
independent of other psychiatric disorders. Genome‐wide association studies (GWAS) on …

Depression and suicide.

MK Nock, AJ Millner, CA Deming, CR Glenn - 2014 - psycnet.apa.org
Suicide is the most concerning possible outcome associated with depression. It is one of the
leading causes of death worldwide and is responsible for more fatalities each year than all …

[PDF][PDF] Genetics of suicide, from genes to behavior

C Crisafulli, R Calati, D De Ronchi, A Sidoti… - Clin …, 2010 - researchgate.net
Suicide is the result of an act deliberately initiated and performed by a person in the full
knowledge or expectation of its fatal outcome, it is one of the leading causes of death among …

The genetics of affective disorder and suicide

P McGuffin, N Perroud, R Uher, A Butlera… - European …, 2010 - cambridge.org
Suicidal behaviour shows evidence of familial clustering and the twin data on completed
suicide suggest moderate heritability. The extent to which the genetics of suicidal behaviour …

A pilot genome wide association and gene expression array study of suicide with and without major depression

H Galfalvy, G Zalsman, YY Huang… - The world journal of …, 2013 - Taylor & Francis
Objectives. Suicide is partly heritable but the responsible genes have not been identified.
We conducted a gene-centric, low coverage single nucleotide polymorphism (SNP) pilot …