Long noncoding RNAs: Potential therapeutic targets in cardiocerebrovascular diseases

H Zhang, B Liu, X Shi, X Sun - Pharmacology & therapeutics, 2021 - Elsevier
Cardiocerebrovascular disease is a collective term for cardiovascular and cerebrovascular
diseases. Because of the complex mechanisms involved in cardiocerebrovascular diseases …

[HTML][HTML] The emerging roles of long noncoding RNAs in common cardiovascular diseases

X Jiang, Q Ning - Hypertension Research, 2015 - nature.com
Long noncoding RNAs (lncRNAs) are defined as noncoding RNAs that are longer than~ 200
nucleotides and lack protein-encoding capacity. It has been shown that lncRNAs are …

[HTML][HTML] The role of long non-coding RNAs in cardiovascular diseases

LTT Le, CXT Nhu - International Journal of Molecular Sciences, 2023 - mdpi.com
Long non-coding RNAs (lncRNAs) are non-coding RNA molecules longer than 200
nucleotides that regulate gene expression at the transcriptional, post-transcriptional, and …

Long noncoding RNAs as diagnostic and therapeutic targets for ischemic stroke

Q Wang, X Liu, R Zhu - Current Pharmaceutical Design, 2019 - ingentaconnect.com
LncRNAs (long non-coding RNAs) are endogenous molecules lacking protein-encoding
capacity, which have been identified as key regulators of ischemic stroke. Increasing …

[HTML][HTML] Long non-coding RNAs: at the heart of cardiac dysfunction?

L Hobuß, C Bär, T Thum - Frontiers in physiology, 2019 - frontiersin.org
During the past decade numerous studies highlighted the importance of long non-coding
RNAs (lncRNAs) in orchestrating cardiovascular cell signaling. Classified only by a …

[HTML][HTML] Long non-coding RNAs as master regulators in cardiovascular diseases

K Archer, Z Broskova, AS Bayoumi, J Teoh… - International journal of …, 2015 - mdpi.com
Cardiovascular disease is the leading cause of death in the United States, accounting for
nearly one in every seven deaths. Over the last decade, various targeted therapeutics have …

Long noncoding RNAs: from clinical genetics to therapeutic targets?

RA Boon, N Jaé, L Holdt, S Dimmeler - Journal of the American College of …, 2016 - jacc.org
Recent studies suggest that the majority of the human genome is transcribed, but only about
2% accounts for protein-coding exons. Long noncoding RNAs (lncRNAs) constitute a …

[HTML][HTML] Expedition to the missing link: Long noncoding RNAs in cardiovascular diseases

CF Yeh, YCE Chang, CY Lu, CF Hsuan… - Journal of Biomedical …, 2020 - Springer
With the advances in deep sequencing-based transcriptome profiling technology, it is now
known that human genome is transcribed more pervasively than previously thought. Up to …

Long noncoding RNAs in cardiovascular disease, diagnosis, and therapy

S Haemmig, V Simion, D Yang, Y Deng… - Current opinion in …, 2017 - journals.lww.com
Long noncoding RNAs in cardiovascular disease, diagnosis, an... : Current Opinion in
Cardiology Long noncoding RNAs in cardiovascular disease, diagnosis, and therapy : Current …

Long non-coding RNA in health and disease

PG Maass, FC Luft, S Bähring - Journal of molecular medicine, 2014 - Springer
Long non-coding RNAs (lncRNAs) interact with the nuclear architecture and are involved in
fundamental biological mechanisms, such as imprinting, histone-code regulation, gene …