Background: The CCR5. 32 polymorphism (a naturally occurring 32-bp deletion in CCR5)
influences the ability of HIV-1 to infect the target cells. Homozygosity for CCR5. 32 prevents …

Humans respond differently toward exposure against pathogens and some individuals are
completely resistant against transmission due to a genetically determined susceptibility. A …

The CC chemokine receptor 5 (CCR5) functions as the major co-receptor for macrophage-
tropic strains of HIV-l [1]. Several polymorphisms identified within the coding and the …

Background Chemokine receptors CCR2 and CCR5 play a key role in immune and
inflammatory responses and have been associated with several diseases, including AIDS. In …

Persons who are homozygous for the Δ32 polymorphism of the CCR5 chemokine receptor
gene are highly protected against human immunodeficiency virus type 1 (HIV-1) infection …

Background: Despite multiple exposure to HIV-1, some individuals remain uninfected. This
resistance has been associated with homozygosity for a 32 base pair deletion in the gene …

The chemokine receptor 5 (CCR5) serves as a fusion cofactor for macrophage-tropic strains
of HIV-1. In addition, CCR5 has been shown to mediate the entry of poxviruses into target …

Seven mutant alleles of the CCR5 gene were identified in southern Chinese, six of which
were novel mutations. The most common was a heterozygous mutant allele (R223Q) found …

CC Chemokine receptor type 5 (CCR5) is expressed on the CD4 T cell surface where
CXCR4 and CCR5 expressions are controlled differently during the activation of T cells and …

ABSTRACT A polymorphism in the gene encoding CCR2 is associated with a delay in
progression to AIDS in human immunodeficiency virus (HIV)-infected individuals. The …