Determination of the CCR5∆ 32 frequency in Emiratis and Tunisians and the screening of the CCR5 gene for novel alleles in Emiratis

SA Al-Jaberi, S Ben-Salem, M Messedi, F Ayadi… - Gene, 2013 - Elsevier
Background The chemokine receptor components play crucial roles in the immune system
and some of them serve as co-receptors for the HIV virus. Several studies have documented …

[PDF][PDF] Low Frequency of CCR5d32 Allele among Greeks in Cyprus

C Christodoulou, M Poullikas… - AIDS research and …, 1997 - researchgate.net
THE HUMAN CHEMOKINE RECEPTOR 5 (CCR5) is the major coreceptor on CD4+ cells for
monocytotropic non-syn cytium-inducing strains of HIV_1. 1-4 It has been shown5-8 that …

Distribution of theCCR5Gene 32-bp Deletion in Europe

G Lucotte, G Mercier - JAIDS Journal of Acquired Immune …, 1998 - journals.lww.com
The chemokine receptor CCR5 constitutes the major coreceptor for the macrophage-tropic
strains of HIV-1. A mutant allele of the CCR5 gene called [DELTA] 32 was shown to provide …

CCR5 promoter haplotypes differentially influence CCR5 expression on natural killer and T cell subsets in ethnically divergent HIV-1 uninfected South African …

ACP Picton, M Paximadis, CT Tiemessen - Immunogenetics, 2012 - Springer
CCR5 plays a critical and central role in HIV-1 infection and, to date, a number of genetic
mutations and haplotypes within the gene have been found to positively or negatively …

Genetic polymorphisms in the open reading frame of the CCR5 gene from HIV-1 seronegative and seropositive individuals from National Capital Regions of India

L Ronsard, V Sood, AS Yousif, J Ramesh, V Shankar… - Scientific reports, 2019 - nature.com
CC chemokine receptor type 5 (CCR5) serves as a co-receptor for Human
immunodeficiency virus (HIV), enabling the virus to enter human CD4 T cells and …

HIV-1 Infection and CCR5Δ32 Homozygosis

E Ballana, JA Esté - Future Virology, 2012 - Taylor & Francis
HIV susceptibility shows a substantial degree of individual heterogeneity, much of which can
be conferred by host genetic variation. Several polymorphisms in the CCR5 gene that …

[HTML][HTML] Rating of CCR5-Delta 32 Homozygous Mutation in Sudanese HIV Patients and Sex Workers

MH Fath-Elrahman, M Alkarsany, BYM Nour… - World Journal of …, 2022 - scirp.org
Background: Prevention against human immunodeficiency virus (HIV) includes natural
resistance in the population; mainly frequency of cysteine-cysteine chemokine receptor type …

Frequency of a mutated CCR-5 allele (delta32) among Italian healthy donors and individuals at risk of parenteral HIV infection

R Zamarchi, S Indraccolo, S Minuzzo… - AIDS research and …, 1999 - liebertpub.com
The aim of this study was to assess the frequency of a truncated allele of the CCR-5 gene
(Delta 32) in Italy, and address its possible role in parenteral HIV transmission, as well as its …

CCR5 Δ32 Heterozygosity Is Associated with an Increase in CXCR4 Cell Surface Expression

S Shalekoff, CT Tiemessen - AIDS research and human …, 2003 - liebertpub.com
EDITOR: CXCR4 and CCR5 are the major coreceptors utilized by HIV-1 to gain entry into
CD4-bearing cells. 1–3 CXCR4 is used by T cell-tropic or X4 HIV-1 strains3 and CCR5 is …

The Latitude Wise Prevalence of the CCR5-Δ32-HIV Resistance Allele in India

I Bhatnagar, M Singh, N Mishra, R Saxena… - Balkan Journal of …, 2009 - sciendo.com
The chemokine receptor CCR5 plays a crucial role during CD4-mediated entry of HIV-1 in
macrophages and a 32 bp deletion in the CCR5 gene (CCR5-∆ 32) confers protection …