Abstract Collagen, chitosan–polycaprolactone (CH–PCL) copolymer with PCL content of
around 40 wt% and chondroitin sulfate (CS) were mixed together at various ratios to prepare …

Abstract Chitosan-polycaprolactone (CH-PCL) copolymers with various PCL percentages
less than 45 wt% were synthesized. Different CH-PCLs were respectively blended with Type …

Cartilage consists of chondrocytes and a special extracellular matrix (ECM) having unique
biochemical, biophysical, and biomechanical properties that play a critical role in the …

The tissue engineering is a promising method for cartilage regeneration studies. The rough
in vivo initial repair environment of articular cartilage is a challenge for the development of …

An ideal scaffold for cartilage tissue engineering should be biomimetic in not only
mechanical property and biochemical composition, but also the morphological structure. In …

Scaffolds with cartilage-like environment and suitable physical properties are critical for
tissue-engineered cartilage repair. In this study, decellularized porcine cartilage-derived …

Background: Cartilage tissue engineering (CTE) aims to obtain a structure mimicking native
cartilage tissue through the combination of relevant cells, three-dimensional scaffolds, and …

The response of mesenchymal stem cells (MSCs) to a matrix largely depends on the
composition as well as the extrinsic mechanical and morphological properties of the …

Chitosan (CHT)/poly (ɛ-caprolactone)(PCL) blend 3D fiber-mesh scaffolds were studied as
possible support structures for articular cartilage tissue (ACT) repair. Micro-fibers were …

Osteoarthritis is the leading cause of pain and disability worldwide. Despite treatment
availability, fully functional and suitable long term treatments for large cartilage defects are …