[HTML][HTML] COVID-19: more than a cytokine storm

G Riva, V Nasillo, E Tagliafico, T Trenti, P Comoli… - Critical care, 2020 - Springer
Background In these first months of coronavirus disease-19 (COVID-19) pandemic, a
mainstream pathogenetic hypothesis, likely stemming from early clinico-therapeutic …

COVID-19: room for treating T cell exhaustion?

G Riva, V Nasillo, E Tagliafico, T Trenti, M Luppi - Critical Care, 2020 - Springer
Dear Editor, Immunosuppressive therapy has emerged as promising therapeutic approach
in the management of Coronavirus disease-19 (COVID-19) patients, who are often …

[HTML][HTML] Cytokine release syndrome is not usually caused by secondary hemophagocytic lymphohistiocytosis in a cohort of 19 critically ill COVID-19 patients

G Lorenz, P Moog, Q Bachmann, P La Rosee… - Scientific reports, 2020 - nature.com
Severe COVID-19 associated respiratory failure, poses the one challenge of our days.
Assessment and treatment of COVID-19 associated hyperinflammation may be key to …

[HTML][HTML] Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19)

B Diao, C Wang, Y Tan, X Chen, Y Liu, L Ning… - Frontiers in …, 2020 - frontiersin.org
Background: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed great threat to human health …

[HTML][HTML] A glimpse into the eye of the COVID-19 cytokine storm

K Kuppalli, AL Rasmussen - EBioMedicine, 2020 - thelancet.com
The pathogenesis of pandemic coronavirus disease-2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely depends heavily on …

The journey of SARS-CoV-2 in human hosts: a review of immune responses, immunosuppression, and their consequences

AF Alshammary, AM Al-Sulaiman - Virulence, 2021 - Taylor & Francis
ABSTRACT Coronavirus disease 2019 (COVID-19) is a highly infectious viral disease
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Laboratory …

Suppressed T cell-mediated immunity in patients with COVID-19: a clinical retrospective study in Wuhan, China

XU Bo, C Fan, A Wang, Y Zou, Y Yu, HE Cong, W Xia… - Journal of Infection, 2020 - Elsevier
Importance An ongoing outbreak of COVID-19 has exhibited significant threats around the
world. We found a significant decrease of T lymphocyte subsets and an increase of …

Humoral immune mechanisms involved in protective and pathological immunity during COVID-19

G Widjaja, AT Jalil, HS Rahman, WK Abdelbasset… - Human Immunology, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 is
associated with excessive inflammation, as a main reason for severe condition and death …

Storm, typhoon, cyclone or hurricane in patients with COVID-19? Beware of the same storm that has a different origin

A Alunno, F Carubbi, J Rodríguez-Carrio - RMD open, 2020 - rmdopen.bmj.com
Some of the articles being published during the severe acute respiratory syndrome–
coronavirus (SARS-CoV)-2 pandemic highlight a link between severe forms of coronavirus …

[HTML][HTML] Severe COVID-19 is characterized by the co-occurrence of moderate cytokine inflammation and severe monocyte dysregulation

B Bonnet, J Cosme, C Dupuis, E Coupez, M Adda… - …, 2021 - thelancet.com
Background SARS-CoV-2 has been responsible for considerable mortality worldwide, owing
in particular to pulmonary failures such as ARDS, but also to other visceral failures and …