Mutations in the fms-like tyrosine kinase 3 (FLT3) gene are detected in approximately one-
third of patients with newly diagnosed acute myeloid leukemia (AML). These consist of the …

The receptor tyrosine kinase fms-like tyrosine kinase 3 (FLT3), involved in regulating
survival, proliferation, and differentiation of hematopoietic stem/progenitor cells, is …

Mutations in the FMS-like tyrosine kinase 3 (FLT3) gene are often present in newly
diagnosed acute myeloid leukemia (AML) patients with an incidence rate of approximately …

Acute myeloid leukemia (AML) is a highly heterogenous disease with multiple signaling
pathways contributing to its pathogenesis. A key driver of AML is the FMS-like tyrosine …

Acute myeloid leukemia (AML) is a cancer of the myeloid lineage of blood cells. Although
significant progress has been made in treating many types of cancers during recent years …

Simple Summary FLT3 mutation is commonly present in newly diagnosed patients with
acute myeloid leukemia, and confers high relapse risk. Targeted therapies with FLT3 …

Internal tandem duplications and tyrosine kinase mutations in the fms-like tyrosine kinase 3
(FLT3) receptor can occur in acute myeloid leukemia (AML) and portend a poor prognosis …

Introduction: Activating mutations of the FMS-like tyrosine kinase 3 (FLT3) gene occur at
high frequency in acute myeloid leukemia (AML), being detected in> 30% of patients at …

Mutations in the FMS-like tyrosine kinase 3 (FLT3) gene are detected in approximately 30%
of acute myeloid leukemia (AML). The high frequency of FLT3 mutations, along with their …

FMS‐like tyrosine kinase 3 (FLT3) is a type III receptor tyrosine kinase that plays an
important role in hematopoietic cell survival, proliferation and differentiation. The most …