Exercise and skeletal muscle ageing: cellular and molecular mechanisms

A McArdle, A Vasilaki, M Jackson - Ageing research reviews, 2002 - Elsevier
As we age, our skeletal muscle becomes smaller and weaker. In addition, the remaining
muscle is more susceptible to damage, particularly following exercise, recovery from …

Exercise, oxidative stress and ageing

A McArdle, MJ Jackson - The Journal of Anatomy, 2000 - cambridge.org
Skeletal muscle has the unique ability to increase the rate of oxygen usage during
contraction. This has led several workers to suggest that by-products of this increased …

Exercise at old age: does it increase or alleviate oxidative stress?

LL Ji - Annals of the New York Academy of Sciences, 2001 - Wiley Online Library
Aging is associated with increased free radical generation in the skeletal muscle that can
cause oxidative modification of protein, lipid, and DNA. Physical activity has many well …

Skeletal muscle damage with exercise and aging

GL Close, A Kayani, A Vasilaki, A McArdle - Sports medicine, 2005 - Springer
Skeletal muscle comprises the largest organ system in the human body and is essential for
force generation and movement. Skeletal muscle is subjected to considerable stresses …

[图书][B] Free radicals in exercise and aging

Z Radák - 2000 - books.google.com
Explore the emerging field of free radical biology, exercise, and aging with this definitive
reference. Free Radicals in Exercise and Agingaddresses the current debate regarding …

Exercise‐induced modulation of antioxidant defense

LL Ji - Annals of the New York Academy of Sciences, 2002 - Wiley Online Library
Maintaining mobility is a critical element for the quality of life. Skeletal muscle, the primary
organ for locomotion, undergoes age‐associated deterioration in size, structure, and …

[HTML][HTML] Skeletal muscle aging: influence of oxidative stress and physical exercise

MJ Gomes, PF Martinez, LU Pagan, RL Damatto… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Skeletal muscle abnormalities are responsible for significant disability in the elderly.
Sarcopenia is the main alteration occurring during senescence and a key public health …

[HTML][HTML] Impaired proteostasis during skeletal muscle aging

R Fernando, C Drescher, K Nowotny, T Grune… - Free Radical Biology …, 2019 - Elsevier
Aging is a complex phenomenon that has detrimental effects on tissue homeostasis. The
skeletal muscle is one of the earliest tissues to be affected and to manifest age-related …

Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness

JG Ryall, JD Schertzer, GS Lynch - Biogerontology, 2008 - Springer
Some of the most serious consequences of ageing are its effects on skeletal muscle. The
term 'sarcopenia'describes the slow but progressive loss of muscle mass with advancing …

[HTML][HTML] Molecular and cellular mechanisms of muscle aging and sarcopenia and effects of electrical stimulation in seniors

L Barberi, BM Scicchitano, A Musaro - European journal of …, 2015 - ncbi.nlm.nih.gov
The prolongation of skeletal muscle strength in aging and neuromuscular disease has been
the objective of numerous studies employing a variety of approaches. It is generally …