Human neuroblastoma cell lines frequently express the TRK-A proto-oncogene and bind
nerve growth factor (NGF) but do not differentiate when exposed to NGF. Transient …

The induction of growth inhibition and differentiation of a glioma cell line by transfection of trk
A cDNA was examined, and production of endogenous nerve growth factor (NGF) also was …

The product of the trk proto-oncogene encodes a receptor for nerve growth factor (NGF).
Here we show that NGF is a powerful mitogen that can induce resting NIH 3T3 cells to enter …

To date more than twenty five different oncogenes have been identified in human
neoplasias. One of these oncogenes is trk, a transforming gene originally isolated from a …

The human trkA cDNA was transfected into a malignant human neuroblastoma (NB) cell line
(HTLA230) to investigate its role in NB growth and differentiation. This cell line lacks …

The trk tyrosine kinase proto-oncogene product gp140p'“'o” k binds nerve growth factor
(NGF) and is rapidly and selectively activated by this neurotrophic factor. To determine …

Summary trkB is a tyrosine protein kinase gene highly related to trk, a proto-oncogene that
encodes a receptor for nerve growth factor (NGF) and neurotrophin-3(NT-3). t&B expression …

Cells that lack the high affinity receptor component (trkA) for nerve growth factor (NGF) are
unresponsive to NGF. We investigated whether C6‐2B cells, a rat glioma derived cell line …

The TRK-T1 oncogene, isolated from a human thyroid carcinoma, represents a rearranged
form of the high affinity nerve growth factor (NGF) receptor encoded by the NTRK1 gene; it is …

We examined events associated with neuronal differentiation of neuroblastoma cell line SH-
SY5Y. Treatment with nerve growth factor (NGF) and aphidicolin, an inhibitor of DNA …