Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19

JK Sun, YT Chen, XD Fan, XY Wang… - Postgraduate …, 2020 - Taylor & Francis
ABSTRACT Coronavirus Disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is spreading worldwide. Antiviral therapy is the …

Impact of hydroxychloroquine/chloroquine in COVID-19 therapy: two sides of the coin

U Fatima, SSA Rizvi, S Fatima… - Journal of Interferon & …, 2020 - liebertpub.com
Coronavirus disease 2019 (COVID-19), which is caused by a novel severe acute respiratory
syndrome coronavirus (SARS-CoV-2), has recently emerged as a global health threat. To …

An updated systematic review of the therapeutic role of hydroxychloroquine in coronavirus disease-19 (COVID-19)

S Das, S Bhowmick, S Tiwari, S Sen - Clinical drug investigation, 2020 - Springer
Abstract Background and Objective The world is currently experiencing the Coronavirus
Disease-19 (COVID-19) pandemic. There is no approved drug for the definitive treatment of …

Chloroquine and hydroxychloroquine in the treatment of COVID-19: the never-ending story

A Gasmi, M Peana, S Noor, R Lysiuk, A Menzel… - Applied microbiology …, 2021 - Springer
The anti-malarial drugs chloroquine (CQ) and hydroxychloroquine (HCQ) have been
suggested as promising agents against the new coronavirus SARS-CoV-2 that induces …

Chloroquine and hydroxychloroquine for the treatment of COVID-19: a systematic review and meta-analysis

A Elavarasi, M Prasad, T Seth, RK Sahoo… - Journal of general …, 2020 - Springer
Background There is no effective therapy for COVID-19. Hydroxychloroquine (HCQ) and
chloroquine (CQ) have been used for its treatment but their safety and efficacy remain …

[PDF][PDF] Pharmacological aspects and clues for the rational use of Chloroquine/Hydroxychloroquine facing the therapeutic challenges of COVID-19 pandemic

F Noël, J Lima - Lat Am J Clin Sci Med Technol, 2020 - sbfte.org.br
Since there is an urgent need for COVID-19 treatment, the pandemic disease caused by
SARS-CoV-2, the repurposing of available drugs is a quick and cheap option, with …

Update on use of chloroquine/hydroxychloroquine to treat coronavirus disease 2019 (COVID-19)

J Gao, S Hu - Bioscience trends, 2020 - jstage.jst.go.jp
Drugs that are specifically efficacious against SARS-CoV-2 have yet to be established.
Chloroquine and hydroxychloroquine have garnered considerable attention for their …

Chloroquine and Hydroxychloroquine: Efficacy in the Treatment of the COVID-19

TC Ho, YH Wang, YL Chen, WC Tsai, CH Lee… - Pathogens, 2021 - mdpi.com
Chloroquine (CQ) and its derivative, hydroxychloroquine (HCQ), have attracted wide
attention for treating coronavirus disease 2019 (COVID-19). However, conflicting outcomes …

A review on possible modes of action of chloroquine/hydroxychloroquine: repurposing against SAR-CoV-2 (COVID-19) pandemic

S Tripathy, B Dassarma, S Roy, H Chabalala… - International journal of …, 2020 - Elsevier
Chloroquine (CQ) and its analogue hydroxychloroquine (HCQ) have long been used
worldwide as frontline drugs for the treatment and prophylaxis of human malaria. Since the …

Chloroquine and hydroxychloroquine for COVID‐19: Perspectives on their failure in repurposing

RR Shah - Journal of clinical pharmacy and therapeutics, 2021 - Wiley Online Library
What is known and Objective Non‐clinical studies suggest that chloroquine (CQ) and
hydroxychloroquine (HCQ) have antiviral activities. Early clinical reports of successful HCQ …