Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review

YJ Surh - Food and Chemical Toxicology, 2002 - Elsevier
A wide variety of phenolic substances derived from spice possess potent antimutagenic and
anticarcinogenic activities. Examples are curcumin, a yellow colouring agent, contained in …

Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF …

YJ Surh, KS Chun, HH Cha, SS Han, YS Keum… - Mutation Research …, 2001 - Elsevier
A wide array of phenolic substances, particularly those present in edible and medicinal
plants, have been reported to possess substantial anticarcinogenic and antimutagenic …

Cancer cell signaling pathways targeted by spice-derived nutraceuticals

B Sung, S Prasad, VR Yadav, BB Aggarwal - Nutrition and cancer, 2012 - Taylor & Francis
Extensive research within the last half a century has revealed that cancer is caused by
dysregulation of as many as 500 different gene products. Most natural products target …

Targeting NOX, INOS and COX‐2 in inflammatory cells: chemoprevention using food phytochemicals

A Murakami, H Ohigashi - International journal of cancer, 2007 - Wiley Online Library
Biological, biochemical and physical stimuli activate inflammatory leukocytes, such as
macrophages, resulting in induction and synthesis of proinflammatory proteins and …

Chronic diseases, inflammation, and spices: how are they linked?

AB Kunnumakkara, BL Sailo, K Banik, C Harsha… - Journal of translational …, 2018 - Springer
Extensive research within the last several decades has revealed that the major risk factors
for most chronic diseases are infections, obesity, alcohol, tobacco, radiation, environmental …

Molecular mechanisms and pathways as targets for cancer prevention and progression with dietary compounds

N Nosrati, M Bakovic, G Paliyath - International journal of molecular …, 2017 - mdpi.com
A unique feature of bioactive food ingredients is their broad antioxidant function.
Antioxidants having a wide spectrum of chemical structure and activity beyond basic …

Molecular approaches toward targeted cancer prevention with some food plants and their products: inflammatory and other signal pathways

AR Khuda-Bukhsh, S Das, SK Saha - Nutrition and cancer, 2014 - Taylor & Francis
In recent years, there has been growing interest in cancer prevention by food plants and
their products. Although several plant parts have potentials for chemoprevention and other …

Molecular targets of nutraceuticals derived from dietary spices: potential role in suppression of inflammation and tumorigenesis

BB Aggarwal, ME Van Kuiken, LH Iyer… - Experimental …, 2009 - journals.sagepub.com
Despite the fact cancer is primarily a preventable disease, recent statistics indicate cancer
will become the number one killer worldwide in 2010. Since certain cancers are more …

Antitumor promoting potential of selected phytochemicals derived from spices: a review

S Rajput, M Mandal - European Journal of Cancer Prevention, 2012 - journals.lww.com
Carcinogenesis is a multistep process exhibiting deregulation in multiple cellular signaling
pathways. Therefore, specific agent based treatments that target only one pathway usually …

Modulation of inflammatory genes by natural dietary bioactive compounds

MH Pan, CS Lai, S Dushenkov… - Journal of agricultural and …, 2009 - ACS Publications
Several epidemiologic studies have shown that chronic inflammation predisposes
individuals to various types of cancer. Many cancers arise from sites of infection, chronic …