Molecular biology and evolution of cancer: from discovery to action

JA Somarelli, H Gardner, VL Cannataro… - Molecular biology …, 2020 - academic.oup.com
Cancer progression is an evolutionary process. During this process, evolving cancer cell
populations encounter restrictive ecological niches within the body, such as the primary …

Evolutionary foundations for cancer biology

CA Aktipis, RM Nesse - Evolutionary applications, 2013 - Wiley Online Library
New applications of evolutionary biology are transforming our understanding of cancer. The
articles in this special issue provide many specific examples, such as microorganisms …

[图书][B] Ecology and evolution of cancer

B Ujvari, B Roche, F Thomas - 2017 - books.google.com
Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a
substantial and original contribution to the fields of evolution, ecology, and cancer, but also …

How cancer shapes evolution and how evolution shapes cancer

M Casás-Selves, J DeGregori - Evolution: Education and outreach, 2011 - Springer
Evolutionary theories are critical for understanding cancer development at the level of
species as well as at the level of cells and tissues, and for developing effective therapies …

Evolutionary determinants of cancer

M Greaves - Cancer discovery, 2015 - AACR
Our understanding of cancer is being transformed by exploring clonal diversity, drug
resistance, and causation within an evolutionary framework. The therapeutic resilience of …

Convergent evolution, evolving evolvability, and the origins of lethal cancer

KJ Pienta, EU Hammarlund, R Axelrod… - Molecular Cancer …, 2020 - AACR
Advances in curative treatment to remove the primary tumor have increased survival of
localized cancers for most solid tumor types, yet cancers that have spread are typically …

Nothing in cancer makes sense except…

M Greaves - BMC biology, 2018 - Springer
Paraphrasing Dobzhansky's famous dictum, I discuss how interrogating cancer through the
lens of evolution has transformed our understanding of its development, causality and …

Genetic and non-genetic mechanisms underlying cancer evolution

Y Shlyakhtina, KL Moran, MM Portal - Cancers, 2021 - mdpi.com
Simple Summary Our manuscript summarizes the up-to-date data on the complex and
dynamic nature of adaptation mechanisms and evolutionary processes taking place during …

Identifying key questions in the ecology and evolution of cancer

AM Dujon, A Aktipis, C Alix‐Panabières… - Evolutionary …, 2021 - Wiley Online Library
The application of evolutionary and ecological principles to cancer prevention and
treatment, as well as recognizing cancer as a selection force in nature, has gained impetus …

Evolutionary biology of cancer

B Crespi, K Summers - Trends in ecology & evolution, 2005 - cell.com
Cancer is driven by the somatic evolution of cell lineages that have escaped controls on
replication and by the population-level evolution of genes that influence cancer risk. We …