MicroRNAs isolated from peripheral blood in the first trimester predict spontaneous preterm birth

EE Winger, JL Reed, X Ji, N Gomez-Lopez, P Pacora… - PLoS …, 2020 - journals.plos.org
Objective To predict spontaneous preterm birth among pregnant women in an African
American population using first trimester peripheral blood maternal immune cell microRNA …

Early first trimester peripheral blood cell microRNA predicts risk of preterm delivery in pregnant women: Proof of concept

EE Winger, JL Reed, X Ji - PLoS One, 2017 - journals.plos.org
Objective We investigated the capacity of first trimester peripheral blood mononuclear cell
(PBMC) microRNA to determine risk of spontaneous preterm birth among pregnant women …

First trimester PBMC microRNA predicts adverse pregnancy outcome

EE Winger, JL Reed, X Ji - American journal of reproductive …, 2014 - Wiley Online Library
Problem Prior to the end of the first trimester, pathogenic mechanisms may commit
pregnancies to adverse outcome such as pre‐eclampsia and miscarriage. A long‐term …

Micro RNA clusters in maternal plasma are associated with preterm birth and infant outcomes

JC Wommack, JP Trzeciakowski, RC Miranda… - PLoS …, 2018 - journals.plos.org
The current study examined micro RNA (miRNAs) clusters from the maternal plasma to
determine their association with preterm birth (PTB) and infant birth outcomes. A subsample …

First-trimester maternal cell microRNA is a superior pregnancy marker to immunological testing for predicting adverse pregnancy outcome

EE Winger, JL Reed, X Ji - Journal of reproductive immunology, 2015 - Elsevier
Patients at risk of immune-mediated pregnancy complications have historically relied on the
use of peripheral blood immunological assays for diagnosis and pregnancy monitoring …

Can microRNA profiling in maternal blood identify women at risk for preterm birth?

MA Elovitz, L Anton, J Bastek, AG Brown - American journal of obstetrics …, 2015 - Elsevier
Objective MicroRNAs (miRNAs), which are highly conserved single-stranded noncoding
RNAs that play a crucial role in gene regulation, have now been identified as important …

Cervical microRNA expression and spontaneous preterm birth

HH Burris, KD Gerson, A Woodward… - American journal of …, 2023 - Elsevier
ABSTRACT BACKGROUND Preterm birth remains a major public health issue affecting 10%
of all pregnancies and increases risks of neonatal morbidity and mortality. Approximately …

A history of preterm delivery is associated with aberrant postpartal MicroRNA expression profiles in mothers with an absence of other pregnancy-related complications

I Hromadnikova, K Kotlabova, L Krofta - International Journal of Molecular …, 2021 - mdpi.com
This prospective cross-sectional case-control study investigated the postpartal gene
expression of microRNAs associated with diabetes/cardiovascular/cerebrovascular …

Second trimester extracellular microRNAs in maternal blood and fetal growth: an exploratory study

RS Rodosthenous, HH Burris, AP Sanders, AC Just… - Epigenetics, 2017 - Taylor & Francis
Healthy feto-maternal communication is critical during pregnancy and is orchestrated by the
placenta. Dysfunction of the placenta leads to fetal growth complications; however, the …

Peripheral blood cell microRNA quantification during the first trimester predicts preeclampsia: Proof of concept

EE Winger, JL Reed, X Ji, K Nicolaides - PLoS One, 2018 - journals.plos.org
Objective We investigated the capacity of microRNAs isolated from peripheral blood buffy
coat collected late during the first trimester to predict preeclampsia. Study design The cohort …