Context: The risks of testosterone therapy in men remain poorly understood. Objective: The
aim of this study was to conduct a systematic review and meta-analyses of testosterone trials …

Context: Low testosterone levels in men have been associated with increased mortality.
However, the influence of testosterone treatment on mortality in men with low testosterone …

Background Testosterone is the standard treatment for male hypogonadism, but there is
uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide …

OBJECTIVE To conduct a systematic review and meta-analysis of randomized trials that
assessed the effect of testosterone use on cardiovascular events and risk factors in men with …

Background Testosterone therapy is increasingly promoted. No randomized placebo-
controlled trial has been implemented to assess the effect of testosterone therapy on …

Description: The American College of Physicians (ACP) developed this guideline to provide
clinical recommendations based on the current evidence of the benefits and harms of …

Purpose We sought to evaluate whether exogenous testosterone therapy is associated with
increased risk of serious cardiovascular events as compared with other treatments or …

Testosterone therapy is increasingly common in the United States, and many of these
prescriptions are written by primary care physicians. There is conflicting evidence on the …

Context Studies of the possible cardiovascular risk of testosterone treatment are
inconclusive. Objective To determine the effect of testosterone treatment on cardiovascular …

Background The cardiovascular safety of testosterone-replacement therapy in middle-aged
and older men with hypogonadism has not been determined. Methods In a multicenter …