For the past 50 years, positive pressure ventilation has been a cornerstone of treatment for
respiratory failure. Consensus surrounding the epidemiology of respiratory failure has …

Respiratory failure complicates most critically ill patients with COVID-19 and is characterized
by heterogeneous pulmonary parenchymal involvement, profound hypoxemia and …

The COVID‐19 pandemic has produced critical shortages of ventilators worldwide. There is
an unmet need for rapidly deployable, emergency‐use ventilators with sufficient functionality …

Background The COVID-19 pandemic revealed a substantial and unmet need for low-cost,
easily accessible mechanical ventilation strategies for use in medical resource-challenged …

We present a low-cost clinically viable ventilator design, AmbuBox, using a controllable
pneumatic enclosure and standard manual resuscitators that are readily available …

Introduction The COVID-19 pandemic has revealed an immense, unmet and international
need for available ventilators. Both clinical and engineering groups around the globe have …

COVID-19 is devastating health systems globally and causing severe ventilator shortages.
Since the beginning of the outbreak, the provision and use of ventilators has been a key …

In the spring of 2020, US regions impacted early by COVID-19, such as northern New Jersey
and New York City, exceeded the usual mechanical ventilation capability at numerous …

Resource-scarce regions with serious COVID-19 outbreaks do not have enough ventilators
to support critically ill patients, and these shortages are especially devastating in developing …

Background The rapidly evolving COVID-19 pandemic has led to increased use of critical
care resources, particularly mechanical ventilators. Amidst growing concerns that the health …