Traumatic brain injury (TBI) is an established risk factor for the early development of
dementia, including Alzheimer's disease, and the post-traumatic brain frequently exhibits …

In at least some individuals who suffer a traumatic brain injury (TBI), there exists a risk of
future neurodegenerative illness. This review focuses on the association between the brain …

Introduction The blood-brain barrier (BBB) is damaged in tauopathies, including progressive
supranuclear palsy (PSP) and Alzheimer's disease (AD), which is thought to contribute to …

Microinfarcts occur commonly in the aging brain as a consequence of diffuse embolic events
and are associated with the development of vascular dementia and Alzheimer9s disease …

Cerebrovascular alterations are a key feature of Alzheimer's disease (AD) pathogenesis.
However, whether vascular damage contributes to synaptic dysfunction and how it …

The cerebral vasculature serves as the crossroads of the CNS, supporting exchange of
nutrients, metabolic wastes, solutes and cells between the compartments of the brain …

Objective The glymphatic system cleans amyloid and tau proteins from the brain in animal
studies of Alzheimer disease (AD). However, there is no direct evidence showing this in …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by the
pathological accumulation of amyloid beta (Aβ) peptides and neurofibrillary tangles …

Traumatic brain injury (TBI) is an increasingly important issue among veterans, athletes and
the general public. Difficulties with sleep onset and maintenance are among the most …

Accumulation of toxic protein aggregates—amyloid-β (Aβ) plaques and
hyperphosphorylated tau tangles—is the pathological hallmark of Alzheimer disease (AD) …