Exploring oncolytic virus-mediated changes in immune microenvironment and immune cells in solid tumors

H Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Oncolytic virus (OV) therapy is a promising cancer treatment strategy, which selectively
replicates in and destroys tumor cells rather than normal cells, thereby effectively releasing …

Innate immunity, tumor microenvironment and oncolytic virus therapy: friends or foes?

MM Stanford, CJ Breitbach, JC Bell… - Current opinion in …, 2008 - europepmc.org
The field of oncolytic virus (OV) therapy is an innovative and evolving science, taking
advantage of the ability of select viruses to preferentially infect and kill human tumor cells …

Remodeling of tumor immune microenvironment by oncolytic viruses

B Zhang, X Wang, P Cheng - Frontiers in Oncology, 2021 - frontiersin.org
Oncolytic viruses (OVs) are potential antitumor agents with unique therapeutic mechanisms.
They possess the ability of direct oncolysis and the induction of antitumor immunity. OV can …

Oncolytic viruses—immunotherapeutics on the rise

BA Keller, JC Bell - Journal of Molecular Medicine, 2016 - Springer
The oncolytic virus (OV) field has entered an exciting period in its evolution in which our
basic understanding of viral biology and anti-cancer potential are being actively translated …

Immune landscape and response to oncolytic virus-based immunotherapy

C Lin, W Teng, Y Tian, S Li, N Xia, C Huang - Frontiers of Medicine, 2024 - Springer
Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer
treatment, offering a unique potential to selectively target malignant cells while sparing …

Cutting both ways: the innate immune response to oncolytic virotherapy

D Mealiea, JA McCart - Cancer Gene Therapy, 2022 - nature.com
Oncolytic viruses (OVs), above and beyond infecting and lysing malignant cells, interact with
the immune system in complex ways that have important therapeutic significance. While …

[HTML][HTML] Armed oncolytic viruses: A kick-start for anti-tumor immunity

JF De Graaf, L de Vor, RAM Fouchier… - Cytokine & growth factor …, 2018 - Elsevier
Oncolytic viruses (OVs), viruses that specifically result in killing tumor cells, represent a
promising class of cancer therapy. Recently, the focus in the OV therapy field has shifted …

[HTML][HTML] Current status and research progress of oncolytic virus

Y Chen, M Tao, X Wu, Z Tang, Y Zhu, K Gong… - Pharmaceutical Science …, 2024 - Elsevier
Oncolytic viruses (OVs) are natural or genetically recombinant viruses that selectively infect
and kill tumor cells without affecting normal cell growth. As a novel type of immunotherapy …

Combination immunotherapy using oncolytic virus for the treatment of advanced solid tumors

CM Oh, HJ Chon, C Kim - International journal of molecular sciences, 2020 - mdpi.com
Oncolytic virus (OV) is a new therapeutic strategy for cancer treatment. OVs can selectively
infect and destroy cancer cells, and therefore act as an in situ cancer vaccine by releasing …

Current clinical landscape of oncolytic viruses as novel cancer immunotherapeutic and recent preclinical advancements

CO Yun, JW Hong, AR Yoon - Frontiers in Immunology, 2022 - frontiersin.org
Oncolytic viruses (OVs) have been gaining attention in the pharmaceutical industry as a
novel immunotherapeutic and therapeutic adjuvant due to their ability to induce and boost …