T Takata, H Isomoto - Internal Medicine, 2024 - jstage.jst.go.jp
Uromodulin, also known as the Tamm-Horsfall protein, is predominantly expressed in epithelial cells of the kidney. It is secreted mainly in the urine, although small amounts are …
R Kirk - Nature Reviews Nephrology, 2014 - nature.com
Novel findings have shown a link between the genetic susceptibility to salt-sensitive hypertension and chronic kidney disease (CKD) and the level of uromodulin expression …
PS Garimella, MJ Sarnak - Current opinion in nephrology and …, 2017 - journals.lww.com
Over the last decade, we have begun to understand the functional role of uromodulin in health and disease. Large prospective studies in generalizable populations are needed to …
C Schaeffer, O Devuyst… - Annual review of …, 2021 - annualreviews.org
Uromodulin, a protein exclusively produced by the kidney, is the most abundant urinary protein in physiological conditions. Already described several decades ago, uromodulin has …
AG Karagiannidis… - Nephrology Dialysis …, 2024 - academic.oup.com
Uromodulin is a kidney-specific glycoprotein which is exclusively produced by the epithelial cells lining the thick ascending limb and early distal convoluted tubule. It is currently …
KA LaFavers, R Micanovic, AR Sabo, LA Maghak… - …, 2022 - Am Heart Assoc
Uromodulin (or Tamm-Horsfall protein) is a glycoprotein uniquely produced in the kidney by tubular cells of the thick ascending limb of the loop of Henle and early distal tubules. This …
S Prajczer, U Heidenreich, W Pfaller… - Nephrology Dialysis …, 2010 - academic.oup.com
Background. Uromodulin (also known as Tamm–Horsfall protein) is the most abundant urinary protein in healthy individuals and exhibits diverse functions including prevention of …
Uromodulin is a nephrospecific protein that is most common in normal urine. And although it has been known for more than 70 years, the function of uromodulin remains unclear …
A Fugiel, M Kuzniewski, D Fedak - Przeglad lekarski, 2013 - europepmc.org
Uromodulin (Tamm-Horsfall protein) is the most abundant protein excreted in the urine under physiological conditions. It is exclusively produced in the kidney and secreted into the …