Cannabidiol and substance use disorder: Dream or reality

S Karimi-Haghighi, Y Razavi, D Iezzi, AF Scheyer… - …, 2022 - Elsevier
Background Cannabidiol (CBD) is one of the major constituents of Cannabis sativa L. that
lacks psychotomimetic and rewarding properties and inhibits the rewarding and reinforcing …

Cannabidiol as an intervention for addictive behaviors: a systematic review of the evidence

M Prud'homme, R Cata… - … abuse: research and …, 2015 - journals.sagepub.com
Drug addiction is a chronically relapsing disorder characterized by the compulsive desire to
use drugs and a loss of control over consumption. Cannabidiol (CBD), the second most …

Role of cannabidiol in the therapeutic intervention for substance use disorders

F Navarrete, MS García-Gutiérrez… - Frontiers in …, 2021 - frontiersin.org
Drug treatments available for the management of substance use disorders (SUD) present
multiple limitations in efficacy, lack of approved treatments or alarming relapse rates. These …

Cannabidiol treatment might promote resilience to cocaine and methamphetamine use disorders: a review of possible mechanisms

C Calpe-López, MP García-Pardo, MA Aguilar - Molecules, 2019 - mdpi.com
Currently, there are no approved pharmacotherapies for addiction to cocaine and other
psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a …

Cannabidiol in the context of substance use disorder treatment: A systematic review

V Paulus, J Billieux, A Benyamina, L Karila - Addictive behaviors, 2022 - Elsevier
Introduction Cannabidiol (CBD) is a phytocannabinoid found in the Cannabis plant. CBD
has received significant medical attention in relation to its anticonvulsant, anxiolytic, and …

Possible receptor mechanisms underlying cannabidiol effects on addictive-like behaviors in experimental animals

E Galaj, ZX Xi - International Journal of Molecular Sciences, 2020 - mdpi.com
Substance use disorder (SUD) is a serious public health problem worldwide for which
available treatments show limited effectiveness. Since the legalization of cannabis and the …

Cannabidiol as a harm reduction strategy for people who use drugs: a rapid review

LA Lo, CA MacCallum, K Nanson… - The Canadian …, 2023 - journals.sagepub.com
Objective The drug poisoning crisis throughout North America necessitates novel harm
reduction approaches. Emerging evidence suggests that cannabidiol (CBD) may have some …

Cannabidiol: pharmacology and therapeutic targets

SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …

[HTML][HTML] Evaluation of the potential use of cannabidiol in the treatment of cocaine use disorder: A systematic review

LA Rodrigues, MES Caroba, FK Taba, R Filev… - Pharmacology …, 2020 - Elsevier
Background Cannabinoids may have an important therapeutic potential for the treatment of
dependence on crack cocaine. Cannabidiol (CBD), in particular, has anxiolytic …

[HTML][HTML] Cannabidiol as a potential treatment for anxiety disorders

EM Blessing, MM Steenkamp, J Manzanares… - …, 2015 - Elsevier
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum
drug that in recent years has drawn increasing interest as a treatment for a range of …