Methylation of the regulatory region of the elongation of very‐long‐chain fatty acids‐like 2
(ELOVL2) gene, an enzyme involved in elongation of long‐chain polyunsaturated fatty …

Epigenetic alterations and metabolic dysfunction are two hallmarks of aging. However, the
mechanism of how their interaction regulates aging, particularly in mammals, remains …

Epigenetic alterations and metabolic dysfunction are two hallmarks of aging. However, the
mechanism of how their interaction regulates aging, particularly in mammals, remains …

purpose. The gene elongation of very long chain fatty acids-4 (ELOVL4) has been shown to
underlie phenotypically heterogeneous forms of autosomal dominant macular degeneration …

Macular degeneration is a heterogeneous group of disorders characterized by
photoreceptor degeneration and atrophy of the retinal pigment epithelium (RPE) in the …

Lipids play essential roles in maintaining cell structure and function by modulating
membrane fluidity and cell signaling. The fatty acid elongase-4 (ELOVL4) protein, expressed …

Elongation of very long chain fatty acids 4 (ELOVL4) is a novel member of the ELO family of
genes that are involved in fatty acid metabolism. ELOVL4 encodes a putative …

All mammalian cell membranes are characterized by amphipathic lipid molecules that
interact with proteins to confer structural and functional properties on the cell. The …

ELOVL4 (elongation of very long chain fatty acids 4) is a member of the ELO family of
proteins involved in the biosynthesis of very long chain fatty acids. Protein truncation …

Mutations in the gene ELOVL4 have been shown to cause stargardt-like macular dystrophy.
ELOVL4 is part of a family of fatty acid elongases and is yet to have a specific elongase …