Recent years have seen the description and elucidation of a new class of anti-inflammatory
and pro-resolving lipid mediators. The arachidonic acid (AA)-derived compounds in this …

Lipoxins and aspirin-triggered lipoxins are lipid mediators generated from arachidonic acid
that act to reduce inflammation and promote resolution. In addition, two new families of lipid …

Inflammation is a physiological defense reaction of living tissues to injury or infection. An
array of mediators, including those derived from omega-6 (omega6) polyunsaturated fatty …

The molecular basis for the beneficial impact of essential omega-3 fatty acids is of
considerable interest. Recently, novel mediators generated from eicosapentaenoic acid …

The enzymatic oxygenation of polyunsaturated fatty acids by lipoxygenases and cyclo‐
oxygenases is a resourceful mode of formation of specific autacoids that regulate the extent …

The molecular basis for the beneficial impact of essential omega-3 (n− 3) FA remains of
interest. Recently, we identified novel mediators generated from eicosapentaenoic acid …

The popular view that all lipid mediators are pro-inflammatory arises largely from the finding
that nonsteroidal anti-inflammatory drugs block the biosynthesis of prostaglandins. The …

Docosahexaenoic acid (C22: 6 n-3, DHA) is the precursor of specialized pro-resolving lipid
mediators (SPMs), such as resolvin, protectin, and maresin families which have been …

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have long been associated with
decreased inflammation and are also implicated in the prevention of tumorigenesis …

The presence of the so‐called “low‐grade” inflammatory state is recognized as a critical
event in adipose tissue dysfunction in obesity. This chronic “low‐grade” inflammation in …