Esophageal squamous cell carcinoma (ESCC) is one of the deadliest forms of human
malignancy that currently lacks approved targeted therapeutics. Accumulating evidence …

The early stages of localized esophageal squamous cell carcinoma (ESCC) can be
effectively treated by surgical resection of the early esophageal cancer, but there is still no …

As a transcription factor critical for embryonic and adult stem cell self-renewal and function,
SOX2 gene amplification has been recognized as a driving factor for various cancers …

The human SOX2 gene was recently identified as a novel major oncogene, recurrently
amplified and overexpressed in esophageal squamous cell carcinoma (ESCC). However …

SOX2 is a master pluripotency controller that was recently identified as a novel major
oncogene, recurrently amplified and activated in Squamous Cell Carcinoma (SCC). These …

SOX2 is highly expressed and controls tumor initiation and cancer stem cell function in
various squamous cell carcinomas including esophageal squamous cancer. However, the …

The transcription factor SOX 2 is essential for the maintenance of embryonic stem cells and
normal development of the esophagus. Our previous study revealed that the SOX2 gene is …

Background: This study aimed to investigate the expression and prognostic significance of
SOX5 in esophageal squamous cell carcinoma (ESCC). Methods: Gene Expression …

Although GSK3β has been reported to have contrasting effects on the progression of
different tumors, it's possible functions in esophageal squamous cell carcinoma (ESCC) and …

Deregulation of SOX9 in esophageal cancer has been reported. However, the regulatory
mechanisms underlying SOX9 during esophageal squamous cell carcinoma (ESCC) …