Low levels of B-type natriuretic peptide predict poor clinical outcomes in patients with chronic and advanced heart failure

T Sun, L Wang - Medical hypotheses, 2007 - Elsevier
B-type natriuretic peptide (BNP) is a neurohormone produced mainly by ventricular
myocytes in response to increased left ventricular end-diastolic pressure. Patients with acute …

Associations of N-terminal pro-B-type natriuretic peptide, estimated glomerular filtration rate, and mortality in US adults

B Ozkan, ME Grams, J Coresh, JW McEvoy… - American heart …, 2023 - Elsevier
Background NT-proBNP is an important predictor of mortality but is inversely related to
estimated glomerular filtration rate (eGFR). Whether the prognostic value of NT-proBNP is …

Subcutaneous administration of the cardiac hormone BNP in symptomatic human heart failure

HH Chen, MM Redfield, LJ Nordstrom, DP Horton… - Journal of cardiac …, 2004 - Elsevier
BACKGROUND: Brain natriuretic peptide (BNP) is a cardiac hormone with vasodilating,
natriuretic, renin-angiotensin-aldosterone–inhibiting and lusitropic properties. We have …

ProBNP1–108 Is Resistant to Degradation and Activates Guanylyl Cyclase-A with Reduced Potency

DM Dickey, LR Potter - Clinical chemistry, 2011 - academic.oup.com
BACKGROUND B-type natriuretic peptide (BNP) compensates for the failing heart and is
synthesized as a 108-residue prohormone that is cleaved to a 32-residue C-terminal …

Head-to-head comparison of B-type natriuretic peptide (BNP) and NT-proBNP in daily clinical practice

J Mair, F Gerda, H Renate, H Ulmer, G Andrea… - International journal of …, 2008 - Elsevier
B-type natriuretic peptide (BNP; Abbott Diagnostics) and N-terminal proBNP (NT-proBNP,
Roche Diagnostics) were compared in consecutive samples of 458 patients (mean age 60 …

Effect of beta-blockade and ACE inhibition on B-type natriuretic peptides in stable patients with systolic heart failure

J Rosenberg, F Gustafsson, WJ Remme… - … drugs and therapy, 2008 - Springer
Introduction The long-term effect of beta-blockade on the plasma levels of natriuretic
peptides BNP and its N-terminal counterpart, NT-proBNP, as risk markers in heart failure …

N-terminal pro-B-type natriuretic peptide in risk stratification of heart failure patients with implantable cardioverter-defibrillator

Y Deng, SJ Cheng, W Hua, MS Cai… - Frontiers in …, 2022 - frontiersin.org
Background The prognostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP)
in heart failure (HF) is well-established. However, whether it could facilitate the risk …

Biological variation of the natriuretic peptides and their role in monitoring patients with heart failure

AHB Wu, A Smith - European journal of heart failure, 2004 - Wiley Online Library
Background: B‐type natriuretic peptide (BNP) and the inactive metabolite NT‐proBNP are
proven tests for diagnosis and staging of severity for patients with heart failure. However, the …

[HTML][HTML] Low Natriuretic Peptide Levels and Outcomes in Patients With Heart Failure and Preserved Ejection Fraction

T Kondo, R Campbell, PS Jhund, IS Anand… - JACC: Heart Failure, 2024 - Elsevier
Background Although some patients with heart failure (HF) with mildly reduced/preserved
ejection fraction have low natriuretic peptide levels, there are no large-scale systematic …

Reduction in BNP levels with treatment of decompensated heart failure and future clinical events

AS Dhaliwal, A Deswal, A Pritchett, D Aguilar… - Journal of cardiac …, 2009 - Elsevier
BACKGROUND: Brain natriuretic peptide (BNP) levels correlate with outcomes in patients
with heart failure (HF). We sought to compare the relationship between absolute and relative …