The human cytomegalovirus

S Landolfo, M Gariglio, G Gribaudo, D Lembo - Pharmacology & …, 2003 - Elsevier
Human cytomegalovirus (HCMV), a betaherpesvirus, represents the major infectious cause
of birth defects, as well as an important pathogen for immunocompromised individuals. The …

The pathogenesis of human cytomegalovirus

P Griffiths, I Baraniak, M Reeves - The Journal of pathology, 2015 - Wiley Online Library
Human cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft
recipient and AIDS patients. More recently, it has been recognized as a pathogen for those …

New therapies for human cytomegalovirus infections

WJ Britt, MN Prichard - Antiviral research, 2018 - Elsevier
The recent approval of letermovir marks a new era of therapy for human cytomegalovirus
(HCMV) infections, particularly for the prevention of HCMV disease in hematopoietic stem …

Cytomegalovirus: pathogen, paradigm, and puzzle

M Boeckh, AP Geballe - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Human cytomegalovirus (CMV), one of the eight herpesviruses that commonly infect
humans, is best known for its propensity to cause disease in immunocompromised patients …

[HTML][HTML] Summary of the II international symposium on cytomegalovirus

MD De Jong, GJ Galasso, B Gazzard, PD Griffiths… - Antiviral research, 1998 - Elsevier
Human cytomegalovirus (HCMV) is a highly species-specific DNA virus belonging to the
Betaherpesvirinae subfamily of the herpesviridae family. Like other herpesviruses, primary …

Pathogenesis of human cytomegalovirus in the immunocompromised host

P Griffiths, M Reeves - Nature Reviews Microbiology, 2021 - nature.com
Human cytomegalovirus (HCMV) is a herpesvirus that infects~ 60% of adults in developed
countries and more than 90% in developing countries. Usually, it is controlled by a vigorous …

Overview of human cytomegalovirus pathogenesis

HL Fulkerson, MT Nogalski, D Collins-McMillen… - … : Methods and Protocols, 2021 - Springer
Human cytomegalovirus (HCMV) is a betaherpesvirus with a global seroprevalence of 60–
90%. HCMV is the leading cause of congenital infections and poses a great health risk to …

Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments

MK Gandhi, R Khanna - The Lancet infectious diseases, 2004 - thelancet.com
After initial infection, human cytomegalovirus remains in a persistent state with the host.
Immunity against the virus controls replication, although intermitent viral shedding can still …

Drug targets in cytomegalovirus infection

G Andrei, E De Clercq, R Snoeck - Infectious Disorders-Drug …, 2009 - ingentaconnect.com
Human cytomegalovirus (HCMV) infections are usually benign and self-limiting in the
immunocompetent population; however, HCMV is a well-recognized problem among …

Antiviral drug resistance of human cytomegalovirus

NS Lurain, S Chou - Clinical microbiology reviews, 2010 - Am Soc Microbiol
The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …