Test characteristics of the aldosterone-to-renin ratio as a screening test for primary aldosteronism

PM Jansen, BJH van den Born, WJ Frenkel… - Journal of …, 2014 - journals.lww.com
Background: The aldosterone-to-renin ratio (ARR) is a widely used screening test for
primary aldosteronism. Current guidelines recommend a cut-off value of 91 pmol/mU …

Screening for primary aldosteronism without discontinuing hypertensive medications: plasma aldosterone-renin ratio

BJ Gallay, S Ahmad, L Xu, B Toivola… - American Journal of …, 2001 - Elsevier
The traditional workup for primary aldosteronism is cumbersome and requires discontinuing
antihypertensive medications, which is inconvenient and potentially dangerous. A simple …

The cutoff value of aldosterone-to-renin ratio for the diagnosis of primary aldosteronism in patients taking antihypertensive medicine

S Niizuma, H Nakahama, K Kamide… - Clinical and …, 2008 - Taylor & Francis
Background. Primary aldosteronism (PA) may account for as much as 6–20% of cases of
refractory hypertension referred to hypertension clinics. Because antihypertensive agents …

Screening for primary aldosteronism on and off interfering medications

X Li, J Liang, J Hu, L Ma, J Yang, A Zhang, Y Jing… - Endocrine, 2024 - Springer
Objective To determine whether antihypertensives will affect diagnostic accuracy of the
aldosterone-to-renin ratio (ARR) to an extent that is clinically relevant. Methods Confirmatory …

[PDF][PDF] The aldosterone-to-renin ratio as a screening test for primary aldosteronism.

PM Jansen, F Boomsma, AH van den Meiracker - THE ROLE OF, 2008 - repub.eur.nl
Since the introduction of the aldosterone-to-renin ratio (ARR) as a screening test for primary
aldosteronism (PA), there has been a marked increase in the reported prevalence of this …

Aldosterone/direct renin concentration ratio as a screening test for primary aldosteronism: a meta-analysis

X Li, R Goswami, S Yang, Q Li - Journal of the Renin …, 2016 - journals.sagepub.com
Objective: The accuracy of aldosterone/direct renin concentration ratio (ADRR) as a
screening test in patients with primary aldosteronism (PA) varies widely across the studies …

Use of plasma aldosterone concentration-to-plasma renin activity ratio as a screening test for primary aldosteronism: a systematic review of the literature

VM Montori, WF Young - Endocrinology and Metabolism Clinics, 2002 - endo.theclinics.com
Objective. We conducted a systematic review of the literature to establish the test
characteristics (sensitivity, specificity, likelihood ratios at different cutoff values) of the …

Analysis of screening and confirmatory tests in the diagnosis of primary aldosteronism: need for a standardized protocol

G Giacchetti, V Ronconi, G Lucarelli… - Journal of …, 2006 - journals.lww.com
Background The upright serum aldosterone/upright plasma renin activity ratio (ARR) has
been recommended as a screening tool for the diagnosis of primary aldosteronism …

Performance of aldosterone-to-renin ratio before washout of antihypertensive drugs in screening of primary aldosteronism

X Liu, S Hao, J Bian, Y Lou, H Zhang… - The Journal of …, 2024 - academic.oup.com
Objective The aim of this study is to evaluate performance of aldosterone-to-renin ratio
(ARR) before washout of antihypertensive drugs as a screening test for primary …

Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity

GL Schwartz, ST Turner - Clinical chemistry, 2005 - academic.oup.com
Background: The ratio of plasma aldosterone concentration to plasma renin activity (PRA) is
considered the screening test of choice for primary aldosteronism. Uncertainty exists …