We describe some recent enhancements introduced in C-ImmSim, a simulator of the
immune system response that we have been developing for a number of years along with …

A system of ordinary differential equations is formulated to describe the pathogenesis of HIV
infection, wherein certain features that have been shown to be important by recent …

This book describes a computational model of the immune system reaction, C-ImmSim. The
book presents the basic model as well as the various customizations to implement the …

The need for anti-HIV-1 vaccines is universally recognized. Although several potential
vaccine formulations are being tested in clinical trials, the complexity of the viral system and …

We use mathematical models to describe the interaction of the immune system with the
human immunodeficiency virus (HIV). Our model includes T-lymphocytes and macrophages …

Recently developed models of the interaction of the human immune system and the human
immunodeficiency virus (HIV) suggest the possibility of using interruptions of highly active …

We present computer simulations of the HIV infection based on a sophisticated cellular
automata model of the immune response. The infection progresses following the well …

In this paper, we sought to identify the CD4+ T-cell dynamics in the course of HIV infection in
response to continuous and intermittent intravenous courses of interleukin-2 (IL-2), the …

The interactions between infectious pathogens and the immune system have been
mathematically modeled for numerous diseases. Human immunodeficiency virus (HIV), the …

During the past 6 years, there have been substantial advances in our understanding of
human immunodeficiency virus 1 and other viruses, such as hepatitis B virus and hepatitis C …