Prognostic bioindicators in severe COVID-19 patients

L Bergantini, E Bargagli, M d'Alessandro, RM Refini… - Cytokine, 2021 - Elsevier
Background Severe acute respiratory syndrome caused by novel coronavirus 2 (SARS-CoV-
2) emerged in Wuhan (China) in December 2019. Here we evaluated a panel of biomarkers …

High serum IL-6 values increase the risk of mortality and the severity of pneumonia in patients diagnosed with COVID-19

JJ Guirao, CM Cabrera, N Jiménez, L Rincón… - Molecular …, 2020 - Elsevier
The clinical presentation of COVID-19 is very heterogeneous, ranging from asymptomatic to
severe, which could lead to the need for mechanical ventilation or even death. We analyzed …

Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study

QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …

Could IL-6 predict the clinical severity of COVID-19?

G Aykal, H Esen, D Seyman… - Turkish Journal of …, 2021 - degruyter.com
Objectives An excessive inflammatory response to SARS-CoV-2 is thought to be a major
cause of disease severity in COVID-19. The aim herein was to determine the prognostic …

Deciphering the balance of IL-6/IL-10 cytokines in severe to critical COVID-19 patients

MB Azaiz, AB Jemaa, W Sellami, C Romdhani… - Immunobiology, 2022 - Elsevier
The severity of COVID-19 is largely determined by the inflammatory response, a “Cytokine
storm,” that involves both pro-and anti-inflammatory cytokines. In the current study we …

[HTML][HTML] Dynamic changes in serum IL-6, IL-8, and IL-10 are associated with the outcome of patients with severe COVID-19 in ICU

J Li, L Rong, R Cui, J Feng, Y Jin, Y Yu, X Chen, R Xu - 2020 - europepmc.org
Background: Biomarkers that would help prognosticate outcomes and guide treatment of
patients with severe coronavirus disease 2019 (COVID-19) are currently required. We aimed …

IL-6 and other biomarkers as predictors of severity in COVID-19

N Broman, K Rantasärkkä, T Feuth, M Valtonen… - Annals of …, 2021 - Taylor & Francis
Objective Cytokine release syndrome is suggested to be the most important mechanism
triggering acute respiratory distress syndrome and end organ damage in COVID-19. The …

Interleukine-6 in critically ill COVID-19 patients: A retrospective analysis

J Gorham, A Moreau, F Corazza, L Peluso… - PLoS …, 2020 - journals.plos.org
Introduction Coronavirus disease 2019 (COVID-19) appeared in China in December 2019
and has spread around the world. High Interleukin-6 (IL-6) levels in COVID-19 patients …

Prognostic role of Interleukin-6/lymphocytes ratio in SARS-CoV2 related pneumonia

L Masotti, E Grifoni, G Pelagalli, E Cioni… - International …, 2022 - Elsevier
Introduction and aim Interleukin-6 to lymphocyte (IL-6/Lym) ratio has been identified as a
potential prognostic tool in patients with SARS-CoV2 related pneumonia. The aim of our …

Serum biomarkers associated with SARS-CoV-2 severity

F de Morais Batista, MAM Puga, PV da Silva… - Scientific Reports, 2022 - nature.com
Immunity with SARS-CoV-2 infection during the acute phase is not sufficiently well
understood to differentiate mild from severe cases and identify prognostic markers. We …