Molnupiravir Use Among Patients with COVID-19 in Real-World Settings: A Systematic Literature Review

J Richmond DiBello, VT Raziano, X Liu… - Infectious Diseases and …, 2024 - Springer
Introduction Molnupiravir (MOV) is an oral antiviral for the treatment of individuals with mild-
to-moderate COVID-19 and at high risk of progression to severe disease. Our objective was …

Real-world experience with molnupiravir during the period of SARS-CoV-2 Omicron variant dominance

R Flisiak, D Zarębska-Michaluk, M Rogalska… - Pharmacological …, 2022 - Springer
Background The real-world effectiveness of molnupiravir (MOL) during the dominance of
Omicron SARS-CoV-2 lineage is urgently needed since the available data relate to the …

Shedding new light on COVID-19 therapeutics during the omicron era: a deeper dive into real-world data

A De Vito, A Colpani, G Madeddu - The Lancet Regional Health …, 2023 - thelancet.com
Ever since the emergence of the SARS-CoV-2 pandemic, the quest for efficacious
therapeutic interventions has become a focal point of international health research, focusing …

Effectiveness of molnupiravir in high-risk patients: a propensity score matched analysis

R Najjar-Debbiny, N Gronich, G Weber… - Clinical infectious …, 2023 - academic.oup.com
Background Molnupiravir was granted emergency use authorization for the treatment of mild
to moderate coronavirus disease 2019 (COVID-19). In this study, we used population-based …

Real-World Utilization of Molnupiravir during the COVID-19 Omicron Surge in Israel

C Weil, T Bergroth, A Eisenberg, YO Whiteside… - Epidemiologia, 2023 - mdpi.com
Molnupiravir (MOV) was introduced in Israel in January 2022 during the SARS-CoV-2
Omicron surge for high-risk patients contraindicated for nirmatrelvir/ritonavir. This …

Real-world effectiveness of molnupiravir and nirmatrelvir/ritonavir among COVID-19 inpatients during Hong Kong's Omicron BA. 2 wave: an observational study

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - medRxiv, 2022 - medrxiv.org
Background Real-world evidence on the effectiveness of oral antivirals in mild-to-moderate
COVID-19 patients is urgently needed. This retrospective cohort study aims to evaluate the …

Real-world clinical outcomes of treatment with molnupiravir for patients with mild-to-moderate coronavirus disease 2019 during the Omicron variant pandemic

Y Suzuki, Y Shibata, H Minemura, T Nikaido… - Clinical and …, 2023 - Springer
It is unclear whether molnupiravir has a beneficial effect on vaccinated patients infected with
the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We …

Why molnupiravir fails in hospitalized patients

AN Brown, Y Lang, J Zhou, EJ Franco, KC Hanrahan… - Mbio, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), has radically altered daily life. Effective antiviral …

Molnupiravir use and 30-day hospitalizations or death in a previously uninfected nonhospitalized high-risk population with COVID-19

AA Butt, P Yan, OS Shaikh, SB Omer… - The Journal of …, 2023 - academic.oup.com
Background Clinical benefit of molnupiravir (MPV) in coronavirus disease 2019 (COVID-19)–
infected subpopulations is unclear. Methods We used a matched cohort study design to …

Molnupiravir in COVID-19: A scoping review

S Kaore, S Atal - Current Drug Research Reviews Formerly …, 2022 - ingentaconnect.com
Background: COVID-19, first detected in Wuhan, China, has evolved into a lifethreatening
pandemic spread across six continents, with the global case count being more than 243 …