Function is more reliable than quantity to follow up the humoral response to the receptor-binding domain of SARS-CoV-2-spike protein after natural infection or COVID …

CA Sariol, P Pantoja, C Serrano-Collazo… - Viruses, 2021 - mdpi.com
Both the SARS-CoV-2 pandemic and emergence of variants of concern have highlighted the
need for functional antibody assays to monitor the humoral response over time. Antibodies …

Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients

AS Iyer, FK Jones, A Nodoushani, M Kelly… - Science …, 2020 - science.org
We measured plasma and/or serum antibody responses to the receptor-binding domain
(RBD) of the spike (S) protein of SARS-CoV-2 in 343 North American patients infected with …

Comprehensive characterization of the antibody responses to SARS-CoV-2 Spike protein finds additional vaccine-induced epitopes beyond those for mild infection

ME Garrett, JG Galloway, C Wolf, JK Logue, N Franko… - Elife, 2022 - elifesciences.org
Background: Control of the COVID-19 pandemic will rely on SARS-CoV-2 vaccine-elicited
antibodies to protect against emerging and future variants; an understanding of the unique …

Dynamics of neutralizing antibody titers in the months after severe acute respiratory syndrome coronavirus 2 infection

KHD Crawford, AS Dingens, R Eguia… - The Journal of …, 2021 - academic.oup.com
Most individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) develop neutralizing antibodies that target the viral spike protein. In this study, we …

A high-throughput cell-and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma

C Fenwick, P Turelli, C Pellaton, A Farina… - Science Translational …, 2021 - science.org
The detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific
antibodies in the serum of an individual indicates previous infection or vaccination …

Longitudinal Variations in Antibody Responses against SARS-CoV-2 Spike Epitopes upon Serial Vaccinations

D Yalcin, SJ Bennett, J Sheehan, AJ Trauth… - International journal of …, 2023 - mdpi.com
The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) impacted healthcare, the workforce, and worldwide socioeconomics. Multi …

Quantitative SARS-CoV-2 spike antibody response in COVID-19 patients using three fully automated immunoassays and a surrogate virus neutralization test

Y Kim, JH Lee, GY Ko, JH Ryu, JH Jang, H Bae… - Diagnostics, 2021 - mdpi.com
Quantitative SARS-CoV-2 antibody assays against the spike (S) protein are useful for
monitoring immune response after infection or vaccination. We compared the results of three …

The receptor binding domain of SARS-CoV-2 spike is the key target of neutralizing antibody in human polyclonal sera

TL Steffen, ET Stone, M Hassert, E Geerling… - BioRxiv, 2020 - biorxiv.org
Natural infection of SARS-CoV-2 in humans leads to the development of a strong
neutralizing antibody response, however the immunodominant targets of the polyclonal …

Sequential analysis of binding and neutralizing antibody in COVID-19 convalescent patients at 14 months after SARS-CoV-2 infection

M Rosati, E Terpos, I Ntanasis-Stathopoulos… - Frontiers in …, 2021 - frontiersin.org
Durability of SARS-CoV-2 Spike antibody responses after infection provides information
relevant to understanding protection against COVID-19 in humans. We report the results of a …

Robust neutralizing antibody levels detected after either SARS-CoV-2 vaccination or one year after infection

S Glöckner, F Hornung, M Baier, S Weis, MW Pletz… - Viruses, 2021 - mdpi.com
Humoral immunity after infection or after vaccination against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has been attributed a key part in mitigating the …