The fundamental subunit of chromatin, the nucleosome, is not a static entity but can move
along DNA via either thermal or enzyme-driven movements. Here we have monitored the …

With nucleosomes being tightly associated with the majority of eukaryotic DNA, it is essential
that mechanisms are in place that can move nucleosomes 'out of the way'. A focus of current …

Impediments to DNA access due to assembly of the eukaryotic genome into chromatin are in
part overcome by the activity of ATP‐dependent chromatin‐remodeling complexes. These …

Nucleosomes at the promoters of genes regulate the accessibility of the transcription
machinery to DNA, and function as a basic layer in the complex regulation of gene …

SWI-SNF is an ATP-dependent chromatin remodeling complex that disrupts DNA-histone
interactions. Several studies of SWI-SNF activity on mononucleosome substrates have …

The structure of the SWI/SNF-remodeled nucleosome was characterized with single base-
pair resolution by mapping the contacts of specific histone fold residues with nucleosomal …

ATP-dependent chromatin remodeling complexes can induce the translocation (sliding) of
nucleosomes in cis along DNA, but the mechanism by which sliding occurs is not well …

The SWI/SNF family of chromatin-remodeling enzymes are important regulators of chromatin
structure in transcriptional activation and in the creation and maintenance of nucleosome …

Chromatin-remodeling complexes regulate access to nucleosomal DNA by mobilizing
nucleosomes in an ATP-dependent manner. In this study, we find that chromatin remodeling …

Nucleosome remodeling by the hSWI/SNF complex and other chromatin remodeling
complexes can cause translocation (sliding) of the histone octamer in cis along DNA …