Ultrafast large-scale chemical sensing with CMOS ISFETs: A level-crossing time-domain approach

Y Liu, TG Constandinou… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
The introduction of large-scale chemical sensing systems in CMOS which integrate millions
of ISFET sensors have allowed applications such as DNA sequencing and fine-pixel …

A 32× 32 ISFET array with in-pixel digitisation and column-wise TDC for ultra-fast chemical sensing

Y Liu, TG Constandinou… - 2019 IEEE International …, 2019 - ieeexplore.ieee.org
This paper presents a 32× 32 ISFET sensing array with in-pixel digitisation for pH sensing.
The in-pixel digitisation is achieved using an inverter-based sensing pixel that is controlled …

A novel pH-to-time ISFET pixel architecture with offset compensation

N Moser, TS Lande, P Georgiou - 2015 IEEE International …, 2015 - ieeexplore.ieee.org
A novel pixel architecture is presented to be part of a pH-based DNA microarray using
ISFETs as chemical sensors. The design, based on APS architectures, performs pulse width …

A TDC based ISFET readout for large-scale chemical sensing systems

K Wang, Y Liu, C Toumazou… - 2012 IEEE Biomedical …, 2012 - ieeexplore.ieee.org
This paper presents a novel ISFET based readout system by minimizing the analogue
instrumentation. Quantization of sensed pH is realized by means of a novel ISFET pH-to …

A robust ISFET pH-measuring front-end for chemical reaction monitoring

Y Hu, P Georgiou - IEEE Transactions on Biomedical Circuits …, 2014 - ieeexplore.ieee.org
This paper presents a robust, low-power and compact ion-sensitive field-effect transistor
(ISFET) sensing front-end for pH reaction monitoring using unmodified CMOS. Robustness …

A 12.8 k current-mode velocity-saturation ISFET array for on-chip real-time DNA detection

N Miscourides, LS Yu… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
This paper presents a large-scale CMOS chemicalsensing array operating in current mode
for real-time ion imaging and detection of DNA amplification. We show that the currentmode …

A 201 mV/pH, 375 fps and 512× 576 CMOS ISFET sensor in 65nm CMOS technology

Y Jiang, X Liu, X Huang, J Guo, M Yan… - 2015 IEEE Custom …, 2015 - ieeexplore.ieee.org
This paper presents a high-gain and large-scale CMOS ion-sensitive field effect transistor
(ISFET) sensor. The high-gain readout is achieved by a novel pH-to-Time-to-Voltage …

A dual-mode large-arrayed CMOS ISFET sensor for accurate and high-throughput pH sensing in biomedical diagnosis

X Huang, H Yu, X Liu, Y Jiang, M Yan… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
Goal: The existing ISFET-based DNA sequencing detects hydrogen ions released during the
polymerization of DNA strands on microbeads, which are scattered into microwell array …

Scaling ISFET instrumentation with in-pixel quantisation to deep submicron technologies

N Moser, TS Lande, P Georgiou - 2016 IEEE Biomedical …, 2016 - ieeexplore.ieee.org
In this paper, we present an investigation of technology scaling applied to pixel architectures
for chemical sensing using Ion-Sensitive Field-Effect Transistors (ISFETs). In particular, we …

A 3600× 3600 large-scale ISFET sensor array for high-throughput pH sensing

Y Cong, M Xu, D Zhao, D Wu - 2017 IEEE 12th International …, 2017 - ieeexplore.ieee.org
This paper presents a large-scale ion-sensitive field effect transistor (ISFET) array chip for
pH sensing. A 3600× 3600-pixel ISFET sensor array and corresponding readout circuitry are …