Background The lack of new anthelmintic agents is of growing concern because it affects
human health and our food supply, as both livestock and plants are affected. Two principal …

Helminthiasis is one of the gravest problems worldwide. There is a growing concern on less
available anthelmintics and the emergence of resistance creating a major threat to human …

Parasitic nematodes infect hundreds of millions of people and farmed livestock. Further,
plant parasitic nematodes result in major crop damage. The pipeline of therapeutic …

Parasitic nematodes infect one quarter of the world's population and impact all humans
through widespread infection of crops and livestock. Resistance to current anthelmintics has …

In the present study, we established a practical and cost-effective high throughput screening
assay, which relies on the measurement of the motility of Caenorhabditis elegans by infrared …

Recent advances in handling and readout have facilitated high-throughput screens with
Caenorhabditis elegans. A new study demonstrates that C. elegans is a useful tool in high …

C. elegans is sensitive to the majority of anthelmintic drugs that are used against parasitic
worm infections of humans and livestock. This has provided the opportunity to use molecular …

For more than four decades, the free-living nematode Caenorhabditis elegans has been
extensively used in anthelmintic research. Classic genetic screens and heterologous …

Parasitic nematodes cause diseases in livestock animals and major economic losses to the
agricultural industry worldwide. Nematodes of the order Strongylida, including Haemonchus …

Parasitic nematodes infect many species of animals throughout the phyla, including
humans. Moreover, nematodes that parasitise plants are a global problem for agriculture. As …