Effects of Silver Nanoparticles on the Liver and Hepatocytes In Vitro

BK Gaiser, S Hirn, A Kermanizadeh… - Toxicological …, 2013 - academic.oup.com
With the increasing use and incorporation of nanoparticles (NPs) into consumer products,
screening for potential toxicity is necessary to ensure customer safety. NPs have been …

Comparison of in vitro toxicity of silver ions and silver nanoparticles on human hepatoma cells

IV Vrček, I Žuntar, R Petlevski, I Pavičić… - Environmental …, 2016 - Wiley Online Library
Scientific information on the potential harmful effects of silver nanoparticles (AgNPs) on
human health severely lags behind their exponentially growing applications in consumer …

Silver nanoparticles: their potential toxic effects after oral exposure and underlying mechanisms–a review

S Gaillet, JM Rouanet - Food and Chemical Toxicology, 2015 - Elsevier
Because of their antimicrobial properties, the use of silver nanoparticles (AgNPs) is
increasing fast in industry, food, and medicine. In the food industry, nanoparticles are used …

Acute toxic effects and gender‐related biokinetics of silver nanoparticles following an intravenous injection in mice

Y Xue, S Zhang, Y Huang, T Zhang… - Journal of Applied …, 2012 - Wiley Online Library
This study evaluated the acute toxicity and biokinetics of intravenously administered silver
nanoparticles (AgNPs) in mice. Mice were exposed to different dosages of AgNPs (7.5, 30 or …

In vitro toxicity of silver nanoparticles at noncytotoxic doses to HepG2 human hepatoma cells

K Kawata, M Osawa, S Okabe - Environmental science & …, 2009 - ACS Publications
Although it has been reported that silver nanoparticles (Ag-NPs) have strong acute toxic
effects to various cultured cells, the toxic effects at noncytotoxic doses are still unknown. We …

Silver nanoparticle-induced oxidative stress-dependent toxicity in Sprague-Dawley rats

AK Patlolla, D Hackett, PB Tchounwou - Molecular and cellular …, 2015 - Springer
Due to the intensive commercial application of silver nanoparticles (Ag-NPs), their health
risk assessment is of great importance. For acute toxicity evaluation of orally administered …

Cytotoxicity and apoptosis induced by silver nanoparticles in human liver HepG2 cells in different dispersion media

Y Xue, T Zhang, B Zhang, F Gong… - Journal of Applied …, 2016 - Wiley Online Library
Abstract Silver nanoparticles (Ag NPs) have been widely used in medical and healthcare
products owing to their unique antibacterial activities. However, their safety for humans and …

Silver nanoparticles induce pro‐inflammatory gene expression and inflammasome activation in human monocytes

A Murphy, A Casey, G Byrne… - Journal of Applied …, 2016 - Wiley Online Library
A complete cytotoxic profile of exposure to silver (AgNP) nanoparticles investigating their
biological effects on the innate immune response of circulating white blood cells is required …

Repeated-dose toxicity and inflammatory responses in mice by oral administration of silver nanoparticles

EJ Park, E Bae, J Yi, Y Kim, K Choi, SH Lee… - Environmental …, 2010 - Elsevier
Toxicity of nanoparticles depends on many factors including size, shape, chemical
composition, surface area, surface charge, and others. In this study, we compared the …

Toxicological evaluation of silver nanoparticles and silver nitrate in rats following 28 days of repeated oral exposure

G Qin, S Tang, S Li, H Lu, Y Wang… - Environmental …, 2017 - Wiley Online Library
The increasing application of silver nanoparticles (AgNPs) has been raising concerns about
their potential adverse effects to human and the environment. However, the knowledge on …