Fc-independent neutralization of SARS-CoV-2 by recombinant human monoclonal antibodies
T Noy-Porat, A Edri, R Alcalay, E Makdasi, D Gur… - bioRxiv, 2021 - biorxiv.org
The use of passively-administered neutralizing antibodies is a promising approach for the
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …
[PDF][PDF] Fc-Independent Protection from SARS-CoV-2 Infection by Recombinant Human Monoclonal Antibodies. Antibodies 2021, 10, 45
T Noy-Porat, A Edri, R Alcalay, E Makdasi, D Gur… - 2021 - academia.edu
The use of passively-administered neutralizing antibodies is a promising approach for the
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …
Fc-modified SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models
M Takeshita, H Fukuyama, K Kamada, T Matsumoto… - bioRxiv, 2022 - biorxiv.org
The use of therapeutic neutralizing antibodies against SARS-CoV-2 infection has been
highly effective. However, there remain few practical antibodies against viruses that are …
highly effective. However, there remain few practical antibodies against viruses that are …
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
Emerging evidence indicates that both neutralizing and Fc-mediated effector functions of
antibodies contribute to protection against SARS-CoV-2. It is unclear whether Fc-effector …
antibodies contribute to protection against SARS-CoV-2. It is unclear whether Fc-effector …
Fc-independent protection from SARS-CoV-2 infection by recombinant human monoclonal antibodies
T Noy-Porat, A Edri, R Alcalay, E Makdasi, D Gur… - Antibodies, 2021 - mdpi.com
The use of passively-administered neutralizing antibodies is a promising approach for the
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection
Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …
infection and have been suggested to be a useful correlate of protection for vaccine clinical …
[HTML][HTML] Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection
SARS-CoV-2 has caused the global COVID-19 pandemic. Although passively delivered
neutralizing antibodies against SARS-CoV-2 show promise in clinical trials, their mechanism …
neutralizing antibodies against SARS-CoV-2 show promise in clinical trials, their mechanism …
Protective non-neutralizing mAbs Ab94 and Ab81 retain high-affinity and potent Fc-mediated function against SARS-CoV-2 variants from Omicron to XBB1. 5
A Izadi, M Godzwon, M Ohlin, P Nordenfelt - bioRxiv, 2023 - biorxiv.org
Antibodies play a central role in the immune defense against SARS-CoV-2. There is
substantial evidence supporting that Fc-mediated effector functions of anti-spike antibodies …
substantial evidence supporting that Fc-mediated effector functions of anti-spike antibodies …
Therapeutic potential of SARS-CoV-2-specific monoclonal antibody CR3022
The spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coupled
with a lack of therapeutics or vaccines, has paralyzed the globe. While significant effort has …
with a lack of therapeutics or vaccines, has paralyzed the globe. While significant effort has …
Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeutics
RV House, TA Broge, TJ Suscovich, DM Snow… - PloS one, 2022 - journals.plos.org
The current global COVID-19 pandemic caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has resulted in a public health crisis with more than 168 million …
coronavirus 2 (SARS-CoV-2) has resulted in a public health crisis with more than 168 million …