[HTML][HTML] COVID-19: systemic pathology and its implications for therapy

Q Shen, J Li, Z Zhang, S Guo, Q Wang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Responding to the coronavirus disease 2019 (COVID-19) pandemic has been an
unexpected and unprecedented global challenge for humanity in this century. During this …

[HTML][HTML] Wuhan to world: the COVID-19 pandemic

A Kumar, R Singh, J Kaur, S Pandey… - Frontiers in cellular …, 2021 - frontiersin.org
COVID-19 is a Severe Acute Respiratory Syndrome (SARS), caused by SARS-CoV-2, a
novel virus which belongs to the family Coronaviridae. It was first reported in December …

[HTML][HTML] Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter …

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

[HTML][HTML] COVID-19 mechanisms in the human body—What we know so far

A Kumar, RK Narayan, P Prasoon, C Kumari… - Frontiers in …, 2021 - frontiersin.org
More than one and a half years have elapsed since the commencement of the coronavirus
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …

[HTML][HTML] The COVID-19 pandemic: a comprehensive review of taxonomy, genetics, epidemiology, diagnosis, treatment, and control

YA Helmy, M Fawzy, A Elaswad, A Sobieh… - Journal of clinical …, 2020 - mdpi.com
A pneumonia outbreak with unknown etiology was reported in Wuhan, Hubei province,
China, in December 2019, associated with the Huanan Seafood Wholesale Market. The …

Transcriptional and proteomic insights into the host response in fatal COVID-19 cases

M Wu, Y Chen, H Xia, C Wang… - Proceedings of the …, 2020 - National Acad Sciences
Coronavirus disease 2019 (COVID-19), the global pandemic caused by SARS-CoV-2, has
resulted thus far in greater than 933,000 deaths worldwide; yet disease pathogenesis …

Pathophysiology of COVID-19: mechanisms underlying disease severity and progression

MK Bohn, A Hall, L Sepiashvili, B Jung… - …, 2020 - journals.physiology.org
The global epidemiology of coronavirus disease 2019 (COVID-19) suggests a wide
spectrum of clinical severity, ranging from asymptomatic to fatal. Although the clinical and …

[HTML][HTML] Pathophysiology and treatment strategies for COVID-19

M Kumar, S Al Khodor - Journal of translational medicine, 2020 - Springer
The outbreak of Coronavirus disease of 2019 (COVID-19) caused by the Severe Acute
Respiratory Syndrome coronavirus 2 (SARS-CoV-2), has posed a serious health threat. The …

[HTML][HTML] Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …

[HTML][HTML] New insights of emerging SARS-CoV-2: epidemiology, etiology, clinical features, clinical treatment, and prevention

G Guo, L Ye, K Pan, Y Chen, D Xing, K Yan… - Frontiers in cell and …, 2020 - frontiersin.org
Since the first reports that the novel coronavirus was showing human-to-human transmission
characteristics and asymptomatic cases, the number of patients with associated pneumonia …