Hepatocellular carcinoma (HCC) is one of the most malignant tumors in Chinese people and
offers poor prognosis. Tumor tissue, like normal tissue, is hierarchically differentiated. Thus …

Hepatocellular carcinoma (HCC) is one of the world's most aggressive diseases and carries
a poor prognosis for patients. Recent evidence suggests that HCC is organized by cancer …

Objective: To clarify the precise characteristics of human hepatic progenitor cells (HPCs) for
future cytotherapy in liver diseases. Methods: Hepatic progenitor-like cells were isolated and …

Liver cancer stem cells (L‐CSCs) are considered to be an important therapeutic target for
hepatocellular carcinoma (HCC). This study provides a new in vitro long‐term culture model …

Widespread use of liver transplantation in the treatment of hepatic diseases is restricted by
the limited availability of donated organs. One potential solution to this problem would be …

Simple Summary Cancer stem cells (CSCs) are known to be highly resistant to conventional
therapeutic approaches, such as chemotherapeutic drugs and radiation. Therefore …

Abstract Background & Aims. Major burdens in the treatment of hepatocellular
carcinoma (HCC) are the high percentage of recurrence and resistance to chemotherapy …

Cancer stem cells (CSCs) are a small subpopulation of cells within tumors with capabilities
of self-renewal, differentiation, and tumorigenicity when transplanted into immune …

Not only tumor progression but also metastasis are the major causes of mortality from a wide
range of cancers, including hepatocellular carcinoma (HCC). In general, tumor cells …

Although the “cancer stem cell (CSC)” hypothesis was first proposed roughly 50years ago,
recent progress in stem cell biology and technologies has successfully achieved the …