Prevention of fatal and nonfatal ischemic heart disease by early treatment of hypertension

S Heyden, G Fodor - Cardiology, 1985 - karger.com
Between 1979 and 1984 two major hypertension intervention studies involving 14,000
patients have demonstrated convincing evidence for the effectiveness of blood pressure …

[引用][C] What are we trying to prevent by controlling hypertension?

MF Oliver - American Heart Journal, 1987 - Elsevier
Coronary heart disease (CHD) is the main cause of death in most developed countries. It
had been hoped that control of raised blood pressure would make a major impact on the …

Antihypertensive therapy, serum lipids, coronary heart disease and hypertension--balancing the risks and benefits of treatment.

MC Houston - Western Journal of Medicine, 1986 - ncbi.nlm.nih.gov
In 1931 a British physician named Hay stated that" the greatest dangerto a man with high
blood pressure lies in its discovery because then some fool is certain to try and reduce …

Implications of the primary prevention trials against coronary heart disease.

WB Kannel - Journal of hypertension. Supplement: Official Journal of …, 1990 - europepmc.org
The bulk of the mortality (60%) in hypertension occurs in those with mild to moderate
elevations of blood pressure, and the chief hazard is coronary disease. Although …

Coronary heart disease in hypertensives: a need to reduce cholesterol

S HEYDEN, KA SCHNEIDER… - International journal of …, 1988 - academic.oup.com
Abstract Heyden S (Department of Community and Family Medicine, Duke University
Medical Centre, Durham, MC 27710, USA), Schneider KA and Fodor G J. Coronary heart …

Treatment of mild hypertension: results of a ten-year intervention trial.

WM Smith - Circulation research, 1977 - europepmc.org
Three hundred and eighty-nine subjects, ages 21-55, with diastolic blood pressures
between 90 and 115 mm Hg were studied prospectively for 7-10 years in a controlled …

Changing hypertension treatment to reduce the overall cardiovascular risk.

NM Kaplan - Journal of hypertension. Supplement: Official Journal of …, 1990 - europepmc.org
The increasing tendency to treat hypertension has markedly reduced stroke mortality but has
not significantly reduced the mortality from coronary heart disease. Many explanations for …

Primary prevention in hypertension. Valid conclusions from observational studies.

AW Hoes, DE Grobbee, J Lubsen - Circulation, 1991 - europepmc.org
Relatively few observational (ie, nonexperimental) studies have been conducted to examine
the role of antihypertensive drug therapy in the primary prevention of coronary heart …

Epidemiological and cost implications of antihypertensive treatment for the prevention of cardiovascular disease.

RH Grimm Jr - Journal of Human Hypertension, 1989 - europepmc.org
The major risk factors for coronary disease are blood pressure, blood lipids and cigarette
smoking. Major advances have been made over the past 20 years in altering these factors …

Treatment of hypertension and ischemic heart disease

G Mancia - Journal of Cardiovascular Pharmacology, 1989 - journals.lww.com
Cardiovascular morbidity and mortality increase as a function of blood pressure, but
antihypertensive treatment reduces the rate of both events, thereby representing a …