Resveratrol for primary prevention of atherosclerosis: Clinical trial evidence for improved gene expression in vascular endothelium

B Agarwal, MJ Campen… - International …, 2013 - internationaljournalofcardiology.com
Resveratrol has been proclaimed as an anti-aging compound to prevent and treat chronic
conditions, including cardiovascular disease, diabetes mellitus and neurodegenerative …

[HTML][HTML] Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice

VW Dolinsky, S Chakrabarti, TJ Pereira, T Oka… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Resveratrol (RESV) is a polyphenol with pleiotropic effects that include reduction of
oxidative stress and increased vascular nitric oxide (NO) production. However, whether or …

Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells

J Schwager, N Richard, F Widmer… - BMC Complementary and …, 2017 - Springer
Background The phenolic substance resveratrol (RES) is a plant metabolite known to
modulate numerous physiological functions and to exert beneficial effects as a cancer …

Trans-but not Cis-resveratrol impairs angiotensin-II–mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated …

C Rius, M Abu-Taha, C Hermenegildo… - The Journal of …, 2010 - journals.aai.org
Abstract Angiotensin II (Ang-II) displays inflammatory activity and is implicated in several
cardiovascular disorders. This study evaluates the effect of cis-and trans (t)-resveratrol …

Resveratrol induces acute endothelium-dependent renal vasodilation mediated through nitric oxide and reactive oxygen species scavenging

KL Gordish, WH Beierwaltes - American Journal of …, 2014 - journals.physiology.org
Resveratrol is suggested to have beneficial cardiovascular and renoprotective effects.
Resveratrol increases endothelial nitric oxide synthase (eNOS) expression and nitric oxide …

Pro-and anti-angiogenesis effects of resveratrol

Y Chen, SH Tseng - in vivo, 2007 - iv.iiarjournals.org
Resveratrol, a natural polyphenol, has a variety of effects including protection against
ischemia-reperfusion injury, and antitumor and chemopreventive action against malignant …

Inhibition of vascular endothelial growth factor-induced angiogenesis by resveratrol through interruption of Src-dependent vascular endothelial cadherin tyrosine …

MT Lin, ML Yen, CY Lin, ML Kuo - Molecular pharmacology, 2003 - ASPET
Resveratrol, a polyphenolic compound found in grapes and other fruits, has been reported
to inhibit angiogenesis with an as yet elusive mechanism. Here, we investigate the detailed …

Cardiovascular protective effects and clinical applications of resveratrol

S Cho, K Namkoong, M Shin, J Park, E Yang… - Journal of Medicinal …, 2017 - liebertpub.com
Resveratrol is a naturally occurring phenol that is generated by plant species following injury
or attack by bacterial and fungal pathogens. This compound was first described as the …

[HTML][HTML] Resveratrol Inhibits TNF-α–Induced Proliferation and Matrix Metalloproteinase Expression in Human Vascular Smooth Muscle Cells

B Lee, SK Moon - The Journal of nutrition, 2005 - Elsevier
Resveratrol (RV), a polyphenolic substance found in grape skin, was suggested to play a
role in preventing the development of atherosclerotic disease. Although RV has …

Antiatherogenic effect of resveratrol attributed to decreased expression of ICAM-1 (Intercellular adhesion Molecule-1) mechanistic link from focal adhesion to …

Y Seo, J Park, W Choi, D Ju Son… - … , and vascular biology, 2019 - Am Heart Assoc
Objective—Increasing evidence shows that resveratrol has antiatherogenic effects, but its
underlying mechanisms are unknown. Thus, we evaluated the molecular mechanisms …