Resveratrol in cardiovascular disease: what is known from current research?

H Wang, YJ Yang, HY Qian, Q Zhang, H Xu, JJ Li - Heart Failure Reviews, 2012 - Springer
Resveratrol is a well-known antioxidant that exists in grape skin/seed, red wine, and the root
of Polygonum cuspidatum, a traditional Chinese and Japanese medicinal material. Studies …

Inhibition of TNF‐α‐mediated endothelial cell–monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans‐3,5,4 …

YH Deng, D Alex, HQ Huang, N Wang… - Phytotherapy …, 2011 - Wiley Online Library
Resveratrol (RSV) has been shown to have anti‐inflammatory activity and to have a
protective role against atherosclerosis. Here it is shown, for the first time, that its derivative …

Resveratrol induces vascular smooth muscle cell differentiation through stimulation of SirT1 and AMPK

AM Thompson, KA Martin, EM Rzucidlo - PloS one, 2014 - journals.plos.org
Phenotypic plasticity in vascular smooth muscle cells (VSMC) is necessary for vessel
maintenance, repair and adaptation to vascular changes associated with aging. De …

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates

JA Mattison, M Wang, M Bernier, J Zhang, SS Park… - Cell metabolism, 2014 - cell.com
Central arterial wall stiffening, driven by a chronic inflammatory milieu, accompanies arterial
diseases, the leading cause of cardiovascular (CV) morbidity and mortality in Western …

Effect of red wine and wine polyphenol resveratrol on endothelial function in hypercholesterolemic rabbits

JG Zou, ZR Wang, YZ Huang… - … journal of molecular …, 2003 - spandidos-publications.com
The effect of red wine and wine polyphenol resveratrol on endothelial function was
investigated in experimental hypercholesterolemic rabbits. Endothelial function as …

[PDF][PDF] Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and …

G Spanier, H Xu, N Xia, S Tobias, S Deng… - J Physiol …, 2009 - researchgate.net
Resveratrol, an important antioxidant found in grapes and wine, is likely to contribute to red
wine's potential to prevent human cardiovascular disease. In addition to its known (direct) …

Pharmacological basis and new insights of resveratrol action in the cardiovascular system

CK Cheng, JY Luo, CW Lau, ZY Chen… - British Journal of …, 2020 - Wiley Online Library
Resveratrol (trans‐3, 4′, 5‐trihydroxystilbene) belongs to the family of natural phytoalexins.
Resveratrol first came to our attention in 1992, following reports of the cardioprotective …

Resveratrol protects against TNF-α-induced injury in human umbilical endothelial cells through promoting sirtuin-1-induced repression of NF-KB and p38 MAPK

W Pan, H Yu, S Huang, P Zhu - PloS one, 2016 - journals.plos.org
Inflammation and reactive oxygen species (ROS) play important roles in the pathogenesis of
atherosclerosis. Resveratrol has been shown to possess anti-inflammatory and antioxidative …

Resveratrol: a natural polyphenol with multiple chemopreventive properties

F Brisdelli, G D'Andrea, A Bozzi - Current drug metabolism, 2009 - ingentaconnect.com
Resveratrol, a naturally occurring polyphenol, shows pleiotropic health beneficial effects,
including antioxidant, anti-inflammatory, anti-aging, cardioprotective and neuroprotective …

Resveratrol mediates anti-atherogenic effects on cholesterol flux in human macrophages and endothelium via PPARγ and adenosine

I Voloshyna, O Hai, MJ Littlefield, S Carsons… - European journal of …, 2013 - Elsevier
Resveratrol is a bioactive molecule used in dietary supplements and herbal medicines and
consumed worldwide. Known cardioprotective and anti-inflammatory properties of …