Resveratrol role in cardiovascular and metabolic health and potential mechanisms of action

Q Xu, LY Si - Nutrition Research, 2012 - Elsevier
Resveratrol is a polyphenolic flavonoid found in a diversity of plants, especially berry fruits
and is a popular nutritional supplement. It is known to have antioxidant, anti-inflammatory …

Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes

E Brâkenhielm, R Cao, Y Cao - The FASEB Journal, 2001 - Wiley Online Library
ABSTRACT Resveratrol (3, 5, 4′‐trihydroxystilbene) is a natural compound found in
several plants, including grapes, peanuts, and pines, and in their related products. Red wine …

Resveratrol: A double-edged sword in health benefits

B Salehi, AP Mishra, M Nigam, B Sener, M Kilic… - Biomedicines, 2018 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) belongs to polyphenols' stilbenoids group,
possessing two phenol rings linked to each other by an ethylene bridge. This natural …

Anti-inflammatory responses of resveratrol

S Das, DK Das - Inflammation & Allergy-Drug Targets (Formerly …, 2007 - ingentaconnect.com
Resveratrol (trans-3, 4', 5-trihydroxystilbene), a natural polyphenolic, non-flavonoid
antioxidant, is a phytoalexin found in many plants including grapes, nuts and berries. Recent …

Effects of resveratrol and other wine polyphenols on vascular function: an update

P Gresele, C Cerletti, G Guglielmini, P Pignatelli… - The Journal of nutritional …, 2011 - Elsevier
Several epidemiologic observations show that moderate wine drinking reduces
cardiovascular morbidity and mortality. Wine contains several polyphenols, and among …

Resveratrol and cardiovascular health–promising therapeutic or hopeless illusion?

PCT Tang, YF Ng, S Ho, M Gyda, SW Chan - Pharmacological research, 2014 - Elsevier
Abstract Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) is a natural polyphenolic compound
that exists in Polygonum cuspidatum, grapes, peanuts and berries, as well as their …

Protective effects of chronic resveratrol treatment on vascular inflammatory injury in streptozotocin-induced type 2 diabetic rats: Role of NF-kappa B signaling

X Zheng, S Zhu, S Chang, Y Cao, J Dong, J Li… - European Journal of …, 2013 - Elsevier
Type 2 diabetes mellitus (T2DM) is associated with an increased risk of macrovascular
disease. Epidemiological studies suggest that plant polyphenol resveratrol (REV) is …

Cardiovascular protective effects of resveratrol

S Bradamante, L Barenghi… - Cardiovascular drug …, 2004 - Wiley Online Library
ABSTRACT Resveratrol (3, 4′, 5‐trihydroxy‐trans‐stilbene), a phytoalexin found in grape
skins, peanuts, and red wine, has been reported to have a wide range of biological and …

Resveratrol for the management of human health: how far have we come? A systematic review of resveratrol clinical trials to highlight gaps and opportunities

K Brown, D Theofanous, RG Britton, G Aburido… - International Journal of …, 2024 - mdpi.com
Resveratrol has long been proposed as being beneficial to human health across multiple
morbidities, yet there is currently no conclusive clinical evidence to advocate its …

Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1

S Fukuda, S Kaga, L Zhan, D Bagchi, DK Das… - Cell biochemistry and …, 2006 - Springer
In our study, resveratrol (polyphenol) has been identified as a very important stimulus/agent
for the induction of new vessel growth. Occlusion of a main coronary depletes the blood …