A functional vascular supply is a key component of any large-scale tissue, providing support
for the metabolic needs of tissue-remodeling cells. Although well-studied strategies exist to …

Vascularization in bone tissues is essential for the distribution of nutrients and oxygen, as
well as the removal of waste products. Fabrication of tissue-engineered bone constructs with …

Abstract 3D bioprinting has begun to show great promise in advancing the development of
functional tissue/organ replacements. However, to realize the true potential of 3D bioprinted …

Vascularization has a pivotal role in engineering successful tissue constructs. However, it
remains a major hurdle of bone tissue engineering, especially in clinical applications for the …

The development of sufficient vascular networks is crucial for the successful fabrication of
tissue constructs for regenerative medicine, as vascularization is essential to perform the …

Bone tissue is a highly vascularized tissue. When constructing tissue‐engineered bone
models, both the osteogenic and angiogenic capabilities of the construct should be carefully …

Vascularization is a fundamental prerequisite for large bone construct development and
remains one of the main challenges of bone tissue engineering. Our current study presents …

When large engineered tissue structures are used to achieve tissue regeneration, formation
of vasculature is an essential process. We report a technique that combines 3D printing with …

Survival of functional tissue constructs of clinically relevant size depends on the formation of
an organized and uniformly distributed network of blood vessels and capillaries. The lack of …

Large bone defects remain an unsolved clinical challenge because of the lack of effective
vascularization in newly formed bone tissue. 3D bioprinting is a fabrication technology with …