Most messenger RNAs in higher eukaryotes are transcribed as precursors containing
intervening sequences (introns). Introns are removed by a sophisticated processing …

The primary transcripts of most nuclear protein-coding genes of eu-karyotes are interrupted
by intervening sequences (or introns) that are removed from the pre-mRNA in a process …

The process of pre-mRNA splicing is fundamental to gene regulation in eukaryotes. Specific
RNA sequences called introns, which do not code for amino acids, are removed during …

Splicing of nuclear precursor messenger RNAs is an important and ubiquitous type of gene
regulation in metazoans. Splicing joins the coding sequences called exons by removing the …

The excision of introns from nuclear mRNA precursors (pre-mRNA) is a fundamental step in
the biogenesis of most mRNAs in eukaryotic cells and occurs prior to the transport of newly …

Recently, cis-acting elements and trans-acting RNA and protein factors necessary for
splicing nuclear pre-mRNAs, group II introns or group III introns, have been discovered, and …

Splicing of precursor mRNAs (pre-mRNA) is an important step during eukaryotic gene
expression. The identification of the actual splice sites and the proper removal of introns are …

The protein-coding regions of most vertebrate genes are split, giving rise to primary
transcripts containing introns and exons; the latter must be spliced in the nucleus to form the …

The biogenesis of mature, functional mRNA in eukaryotes often requires the precise
excision of noncoding, intervening sequences (ie, introns) which are present in the …

Pre-mRNA splicing is a fundamental process required for the expression of most metazoan
genes. It is carried out by the spliceosome, which catalyzes the removal of non-coding …