Melanin protects the skin against DNA damage induced by direct absorption of sunlight's UV
radiation. Yet, irradiating melanin in vitro or in cultured cells also generates active oxygen …

Melanin is both photosensitizer and photoprotector. Skin cancer rates decrease with
increasing constitutive pigmentation, yet the pigment has been shown to be photoreactive …

When melanin absorbs light energy, it can produce potentially damaging active oxygen
species. There is little doubt that constitutive pigment in dark-skinned individuals is …

Ultraviolet (UV)-induced skin cancers, including melanomas and basal/squamous cell
carcinomas, occur more frequently in individuals with fair skin than in those with dark skin …

Melanin plays an important role in protecting the skin against UV radiation, and melanomas
and basal/squamous cell carcinomas occur more frequently in individuals with fair/light skin …

Epidermal melanin pigment is believed to prevent development of ultraviolet (UV)–induced
skin cancer by shielding cell nuclei and reducing DNA damage formation. It has not been …

Melanin is thought to serve in photoprotection. To investigate this, we have compared the
responses of cultured human melanocytes derived from different pigmentary phenotypes …

Highly pigmented, dark skin is more resistant to the harmful effects of solar ultraviolet
radiation than light-colored human skin. The extent to which tanning protects skin from …

The question of whether melanins are photoprotecting and/or photosensitizing in human
skin cells continues to be debated. To evaluate the role of melanin upon UVA irradiation …

The goal of this investigation was to correlate the melanin content in human pigmentary cells
with the generation of UVB‐induced photoproducts and to examine the relationship between …