[HTML][HTML] Advancements in CRISPR-based biosensing for next-gen point of care diagnostic application

A Kumaran, N Jude Serpes, T Gupta, A James… - Biosensors, 2023 - mdpi.com
With the move of molecular tests from diagnostic labs to on-site testing becoming more
common, there is a sudden rise in demand for nucleic acid-based diagnostic tools that are …

Progress and bioapplication of CRISPR-based one-step, quantitative and multiplexed infectious disease diagnostics

Y Shen, K Hu, M Yuan, G Duan, Y Guo… - Journal of Applied …, 2023 - academic.oup.com
Abstract In Vitro Diagnosis (IVD) technology is able to accurately detect pathogens or
biomarkers at an initial stage of disease, which works as an important toolbox for disease …

CRISPR-based biosensors for human health: A novel strategy to detect emerging infectious diseases

Y He, Q Hu, S San, T Kasputis, MGD Splinter… - TrAC Trends in …, 2023 - Elsevier
Infectious diseases (such as sepsis, influenza, and malaria), caused by various pathogenic
bacteria and viruses, are widespread across the world. Early and rapid detection of disease …

CRISPR-based biosensing systems: a way to rapidly diagnose COVID-19

M Vatankhah, A Azizi… - Critical reviews in …, 2021 - Taylor & Francis
The outbreak of the emerging SARS-CoV-2 virus has highlighted the challenges of detecting
viral infections, especially in resource-limited settings. The SARS-CoV-2 virus transmission …

Nucleic acid detection using CRISPR/Cas biosensing technologies

R Aman, A Mahas, M Mahfouz - ACS synthetic biology, 2020 - ACS Publications
For infectious diseases, rapid and accurate identification of the pathogen is critical for
effective management and treatment, but diagnosis remains challenging, particularly in …

CRISPR-based detection of SARS-CoV-2: A review from sample to result

R Nouri, Z Tang, M Dong, T Liu, A Kshirsagar… - Biosensors and …, 2021 - Elsevier
The current pandemic of the 2019 novel coronavirus (COVID-19) caused by SARS-CoV-2
(severe acute respiratory syndrome coronavirus-2) has raised significant public health …

[HTML][HTML] Powerful CRISPR-based biosensing techniques and their integration with microfluidic platforms

B Chen, Y Li, F Xu, X Yang - Frontiers in bioengineering and …, 2022 - frontiersin.org
In the fight against the worldwide pandemic coronavirus disease 2019 (COVID-19), simple,
rapid, and sensitive tools for nucleic acid detection are in urgent need. PCR has been a …

[HTML][HTML] CRISPR-cas technology: A key approach for SARS-CoV-2 detection

L Fang, L Yang, M Han, H Xu, W Ding… - … in bioengineering and …, 2023 - frontiersin.org
The CRISPR (Clustered Regularly Spaced Short Palindromic Repeats) system was first
discovered in prokaryotes as a unique immune mechanism to clear foreign nucleic acids. It …

Pathogen detection strategy based on CRISPR

Y Tian, T Liu, C Liu, Q Xu, Q Liu - Microchemical Journal, 2022 - Elsevier
Accurate and rapid detection of pathogens is essential for food safety, epidemic prevention,
disease diagnosis and environmental monitoring. So far, many CRISPR/Cas systems have …

CRISPR-based biosensors for pathogenic biosafety

H Yang, R Ledesma-Amaro, H Gao, Y Ren… - Biosensors and …, 2023 - Elsevier
Pathogenic biosafety is a worldwide concern. Tools for analyzing pathogenic biosafety, that
are precise, rapid and field-deployable, are highly demanded. Recently developed …