The ongoing COVID-19 pandemic is one of the biggest health challenges of recent decades.
Among the causes of mortality triggered by SARS-CoV-2 infection, the development of an …

ABSTRACT COVID-19 is often related to hyperinflammation that drives lung or multiorgan
injury. The immunopathological mechanisms that cause excessive inflammation are under …

Covid-19 is often related to hyperinflammation that drives lung or multi-organ injury. The
immunopathological mechanisms that cause excessive inflammation following SARS-Cov-2 …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has emerged as a
pandemic. Paucity of information concerning the virus and therapeutic interventions have …

The outbreaks of 2019 novel coronavirus disease (COVID-19) caused by SARS-CoV-2
infection has posed a severe threat to global public health. It is unclear how the human …

The term cytokine storm refers to an uncontrolled overproduction of soluble inflammatory
markers known as cytokines and chemokines. Autoimmune destruction of the lungs …

Inflammation is an intrinsic defence mechanism triggered by the immune system against
infection or injury. Chronic inflammation allows the host to recover or adapt through cellular …

To identify key gene expression pathways altered with infection of the novel coronavirus
SARS-CoV-2, we performed the largest comparative genomic and transcriptomic analysis to …

The pathophysiology of coronavirus disease 19 (COVID-19) involves a multitude of host
responses, yet how they unfold during the course of disease progression remains unclear …

Motivation COVID-19 has several distinct clinical phases: a viral replication phase, an
inflammatory phase and in some patients, a hyper-inflammatory phase. High mortality is …