Endotheliitis and endothelial dysfunction in patients with COVID-19: its role in thrombosis and adverse outcomes

W Mosleh, K Chen, SE Pfau, A Vashist - Journal of Clinical Medicine, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV2), emerging in Wuhan, China and …

[HTML][HTML] Endothelial dysfunction in COVID-19: Current findings and therapeutic implications

MP Nägele, B Haubner, FC Tanner, F Ruschitzka… - Atherosclerosis, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) increases the risk of several non-pulmonary
complications such as acute myocardial injury, renal failure or thromboembolic events. A …

[HTML][HTML] Endothelial dysfunction contributes to COVID-19-associated vascular inflammation and coagulopathy

J Zhang, KM Tecson, PA McCullough - Reviews in cardiovascular …, 2020 - imrpress.com
Great attention has been paid to endothelial dysfunction (ED) in coronavirus disease 2019
(COVID-19). There is growing evidence to suggest that the angiotensin converting enzyme 2 …

Endothelial dysfunction and SARS-CoV-2 infection: association and therapeutic strategies

H Deng, TX Tang, D Chen, LS Tang, XP Yang… - Pathogens, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), has been recently considered a systemic disorder leading to …

[HTML][HTML] Endothelial contribution to COVID-19: an update on mechanisms and therapeutic implications

Z Ma, KY Yang, Y Huang, KO Lui - Journal of Molecular and Cellular …, 2022 - Elsevier
The global propagation of SARS-CoV-2 leads to an unprecedented public health
emergency. Despite that the lungs are the primary organ targeted by COVID-19, systemic …

Systemic arterial thrombosis and acute mesenteric ischemia in a patient with COVID-19

E Azouz, S Yang, L Monnier-Cholley, L Arrivé - Intensive care medicine, 2020 - Springer
A 56-year-old patient was admitted in our institution for an acute ischemic stroke due to the
occlusion of the right middle cerebral artery. Angio-CT scan performed upon admission …

Pathophysiological association of endothelial dysfunction with fatal outcome in COVID-19

T Maruhashi, Y Higashi - International Journal of Molecular Sciences, 2021 - mdpi.com
The outbreak of coronavirus disease 2019 (COVID-19) caused by the betacoronavirus
SARS-CoV-2 is now a worldwide challenge for healthcare systems. Although the leading …

The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection

S Pons, S Fodil, E Azoulay, L Zafrani - Critical care, 2020 - Springer
In severe SARS-CoV-2 infections, emerging data including recent histopathological studies
have emphasized the crucial role of endothelial cells (ECs) in vascular dysfunction …

Endothelial dysfunction in COVID-19: potential mechanisms and possible therapeutic options

MC Pelle, I Zaffina, S Lucà, V Forte, V Trapanese… - Life, 2022 - mdpi.com
SARS-CoV-2, a novel coronavirus found in Wuhan (China) at the end of 2019, is the
etiological agent of the current pandemic that is a heterogeneous disease, named …

Is the endothelium the missing link in the pathophysiology and treatment of COVID-19 complications?

P Castro, M Palomo, AB Moreno-Castaño… - … drugs and therapy, 2022 - Springer
Patients with COVID-19 present a wide spectrum of disease severity, from asymptomatic
cases in the majority to serious disease leading to critical care and even death. Clinically …